Founded by Chris Mirabile, Novos Labs is based in New York and offers science-backed formulas that support the healthy aging process. Its product line includes options like Novos Boost, Novos Vital, and Novos Age.
Novos offerings combine supplements, tools, and texts, which may help target the biological root causes of aging. The brand aims to help maintain energy, mental clarity, youthful skin, and energy levels. However, does Novos actually deliver on its claims?
In this exclusive Novos review, we will explore the options featured by Novos, its benefits, and disadvantages. We will also evaluate the brand's credibility to help you make an informed decision.
Novos claims to help in managing aging symptoms by targeting the hallmarks of aging, which include genomic instability, telomere attrition, and epigenetic alterations. These hallmarks also include loss of proteostasis, deregulated nutrient sensing, stem cell exhaustion, mitochondrial dysfunction, and cellular senescence.
According to the official website, the Novos Scientific Advisory Board includes internationally recognized experts like Dr. George Church (Harvard geneticist) and Dr. Matt Kaeberlein (biogerontologist known for work on mTOR and rapamycin).
The brand also features the Novos Life app, which delivers personalized longevity recommendations, and FaceAge, an AI-powered facial age estimation tool based on dermatological and biometric analysis.
Novos Boost is a longevity formula by Novos Labs, which may help increase levels of nicotinamide adenine dinucleotide (NAD⁺), a molecule essential for energy production, DNA repair, and cellular resilience, which naturally declines with age. This formula combines ultra-pure nicotinamide mononucleotide (NMN), at a dosage of 250 mg per daily serving (2 capsules), with a purity of over 99%, verified by third-party lab testing to ensure safety and effectiveness. NMN is a precursor to NAD⁺ and plays a key role in supporting sirtuin activation, mitochondrial health, and cellular repair mechanisms.
As per the official website, Novos Boost capsules are made to be vegan, gluten-free, sugar-free, and contain no artificial fillers or preservatives. The makers state that Novos Boost can be swallowed whole or opened to administer the NMN powder sublingually (under the tongue) for quicker absorption into the bloodstream, bypassing digestion. The brand also suggests taking two capsules per day, either in the morning or divided between morning and afternoon.
Novos Age is a scientifically advanced, at-home biological age testing kit by Novos. This test aims to provide you with a detailed analysis of how you are aging biologically. Using a small blood sample collected through a simple finger-prick, Novos Age evaluates several key biomarkers to generate a personalized aging profile.
As per the manufacturer, Novos Age features the DunedinPACE Rate of Aging Clock, an epigenetic tool developed by researchers at Duke and Columbia Universities, which measures the speed at which you are currently aging. This test also includes an Organ Age Analysis, which assesses the biological age of different organ systems, and a Telomere Length Assessment, providing insight into cellular aging through the length of telomeres, which naturally shorten as we age.
The makers mention that once the sample is mailed to a certified lab, you will receive a comprehensive, 55-page report within about four weeks. This report outlines your biological age and also offers personalized recommendations for improving healthspan and longevity.
According to the official website, Novos Age integrates with the Novos Life mobile app, allowing you to track your Lifestyle Score, receive personalized health advice, adopt daily longevity-promoting habits, and even get guidance from an AI chatbot.
Novos Core+Boost bundle combines Novos Core with Novos Boost. Novos Core in this bundle combines fisetin, a senolytic flavonoid known to selectively clear senescent cells, which contribute to inflammation and tissue dysfunction with age.
The Novos Core+Boost by Novos also features Novos Boost, which may support mitochondrial energy metabolism, sirtuin activation, and DNA repair via PARP enzymes.
Novos Core is an anti-aging formula that may help target the causes of aging, such as genomic instability, telomere attrition, epigenetic alterations, and mitochondrial dysfunction. This formula combines Calcium Alpha-Ketoglutarate (AKG), which the studies show can help extend lifespan and healthspan in mice by modulating inflammation and influencing epigenetic markers. Fisetin, a flavonoid found in strawberries, is also included in Novos Core for its senolytic properties, selectively clearing senescent cells, which contribute to age-related tissue dysfunction.
The makers state that adding pterostilbene, a methylated derivative of resveratrol, to Novos Core might offer higher bioavailability and help activate sirtuin pathways involved in DNA repair and metabolic regulation.
According to the official website, Novos Core has vitamin C and magnesium malate, which could support mitochondrial health and oxidative stress reduction, both of which are central to slowing age-related decline.
According to the official website, Novos Vital targets age-related decline in key organs like the brain, heart, liver, kidneys, gut, muscles, and eyes. It is said to influence mitochondrial dysfunction, cellular senescence, chronic inflammation, and loss of proteostasis.
As per the makers, Novos Vital combines 4 grams of trehalose, a sugar known to induce autophagy by activating transcription factor EB (TFEB), thereby promoting the clearance of misfolded proteins and cellular components, which is especially important for neuroprotection and cognitive longevity. It also contains 2 grams of acetic acid (from apple cider vinegar), which activates AMPK, a key metabolic sensor that improves lipid metabolism, insulin sensitivity, and reduces systemic inflammation.
Novos Vital by Novos also uses nattokinase (200 mg), an enzyme extracted from fermented soybeans. This enzyme might support cardiovascular and cerebrovascular health by promoting fibrinolysis, reducing blood viscosity, and mitigating oxidative stress.
The addition of 560 mg of rutin, a polyphenolic antioxidant, in this formula could also help protect muscle tissue from oxidative damage, support mitochondrial health, and enhance recovery and mobility with age.
The Novos Longevity Kit may help optimize biological age and improve vitality by targeting the root causes of aging at the cellular level. It includes Novos Core, Novos Boost, and Novos Age. Novos Core combines 13 scientifically backed ingredients, including calcium alpha-ketoglutarate, glycine, pterostilbene, fisetin, and malate. This kit also features Novos Boost, which might support energy metabolism, DNA repair, and maintaining cellular function. According to the official website, the Novos Longevity Kit by Novos includes Novos Age, which is a biological age test based on epigenetic markers, providing a detailed analysis of your biological age and the pace at which you are aging.
Novos claims to target all 12 known causes of aging by using ingredients like calcium alpha-ketoglutarate, fisetin, magnesium malate, and glycine in its offerings. These ingredients are backed by intense scientific research and are known to help improve cellular health, reduce inflammation, and boost mitochondrial function. As per the official website, the Novos product line is developed by a team of scientists and medical experts from leading institutions like Harvard Medical School, MIT, and the Salk Institute. Their expertise ensures that every ingredient in Novos Core is backed by science.
According to the official website, Novos manufactures its products in the U.S. using carefully selected ingredients from reliable global sources. The makers state that each ingredient undergoes third-party testing to confirm its purity and strength, so you know exactly what you're getting. The brand also claims to choose ingredient forms that are supported by research and easier for your body to absorb, like calcium alpha-ketoglutarate and magnesium malate. These choices reflect Novos's focus on effectiveness, not just filling a formula. Novos shares its ingredient lists, testing results, and sourcing details openly on its website. This level of transparency makes it easier for you to make informed decisions about the supplements you use.
Novos claims to be the only over-the-counter natural supplement brand to be a member of the Longevity Biotech Association, a leading consortium in the field of aging and biotechnology. This exclusive recognition shows that Novos is also respected within the biotech industry. Membership is typically reserved for companies with strong scientific credibility and innovation. Novos's acceptance into the association indicates its position as a trusted brand in consumer longevity options.
Novos features the Novos Life App, which enables you to track your biological age, lifestyle habits, and supplement routine, creating a personalized longevity dashboard. It is free and scientifically grounded, helping you measure the impact of your lifestyle and product use over time. The brand also supports HSA and FSA payments, making it easier for you to invest in long-term health with tax-advantaged dollars. With subscription plans offering up to 27 percent savings, Novos maintains a good balance between premium quality and affordability for regular use.
Novos has a return policy that could disadvantage potential customers. They only accept returns for unopened items within 30 days of purchase. There is a $25 shipping fee and a $35 restocking fee. For example, if you buy a product for $44, these fees could end up costing more than the refund, leaving you with no money back. This strict policy may discourage people from trying Novos products, especially in the health and wellness industry. Health products can work differently for each person, so customers often want to try them before committing. The added cost of returning a product may make people hesitant to buy, as they may not want to risk losing money if the product doesn't work for them.
Novos features products like Novos Vital, which includes inulin, a prebiotic fiber that can cause bloating, gas, diarrhea, and cramps, particularly in people to fiber or when taken in more significant amounts. This product by Novos has nattokinase, an enzyme derived from fermented soy. While nattokinase offers cardiovascular benefits, it can trigger allergic reactions in people with soy sensitivities. Symptoms can include mild discomfort to more severe responses like vomiting and diarrhea.
Novos Labs and Qualia Life Sciences both focus on health optimization and longevity, but they take different approaches.
Qualia Life Sciences adopts a holistic and performance-driven approach to health optimization. Their products, like Qualia Mind and Qualia NAD+, may enhance cognitive function, energy levels, and mitochondrial health. Rather than focusing on aging, Qualia takes a broad systems-based view, optimizing brain function, metabolism, and vitality through synergistic ingredients. While Qualia's approach is supported by scientific research, it is more focused toward performance enhancement alongside longevity, making it appealing for adults over 35 who are interested in boosting cognitive performance and energy while supporting long-term health. Unlike Novos, Qualia does not offer a tool like Novos Age to track biological age but instead focuses on comprehensive supplementation.
Novos is primarily dedicated to targeting the biological root causes of aging, with a strong emphasis on slowing down or reversing the aging process. The brand's product line includes Novos Core, which is made to address aging mechanisms like mitochondrial dysfunction and genomic instability.
Novos offers evidence-backed, highly targeted supplements and tools like the Novos Age epigenetic test, which allows you to track your biological age and the effectiveness of your supplementation routine.
Novos Labs and Life Extension both operate in longevity and health optimization, but they differ in their approaches, product offerings, and target audiences.
Novos Labs is focused on scientifically backed anti-aging options. The brand claims to use research to formulate supplements that target specific mechanisms, aiming to extend both lifespan and healthspan. Novos features products like Novos Boost (which raises NAD+ levels) and tools like Novos Age, an epigenetic test for tracking biological age, demonstrate the company's emphasis on personalized, data-driven anti-aging strategies. Their approach is deeply rooted in advanced geroscience, focusing on biological age optimization through targeted supplementation and tracking.
In contrast, Life Extension has a broader approach to health and wellness, focusing not only on longevity but also on general health across various categories. It claims to offer over 300 products, ranging from anti-aging supplements to those supporting heart health, brain function, immune support, and joint health. While Life Extension also offers NAD+ precursors like NMN and nicotinamide riboside (NR), they take a wide-ranging approach, targeting different aspects of health rather than focusing solely on aging.
Life Extension's product range is extensive, covering various health areas, while Novos Labs focuses intensely on anti-aging research with a clear emphasis on longevity.
To evaluate Novos, we looked at several key factors such as brand age, background, customer reviews, and third-party ratings. Novos is a relatively new company in the longevity supplement space, built around a science-driven approach to slowing aging. While it claims to promote transparency and actively engages with the biohacking community, its short time on the market limits its long-term credibility compared to older, more established brands.
We also considered customer feedback on Trustpilot, where Novos has a 3.8 out of 5 rating based on 90+ reviews. This score suggests a mix of experiences, such as many customers being satisfied, but others having voiced concerns. The limited number of reviews makes it harder to assess the brand's consistency over time, but the overall sentiment is moderately positive.
In contrast, the Better Business Bureau (BBB) rating raises some red flags. Novos currently holds a C-grade, with three complaints filed and one left unresolved. Failing to respond to customer complaints can indicate issues in communication or support, which is especially important to note for a health-related product.
We looked closely at recent customer reviews on Trustpilot to get a real-world view of how Novos performs. Most users who consistently took products like Novos Core and Boost reported noticeable improvements in energy, mood, and skin health. These reviewers often emphasized their trust in the science behind the brand and appreciated the structured, research-driven approach Novos brings to longevity supplements.
At the same time, there were clear areas where the experience fell short for some. Several users disliked the taste and texture of the unflavored Core powder or the Vitals gummies, finding them difficult to take daily. Others raised concerns about customer service and shipping, ranging from delivery delays to issues with refunds and product returns. A few consumers even described their experience as frustrating or misleading, especially when involving third-party delivery services.
We compared Novos's Vital Formula pricing with similar products to assess its value for money. At $69 for 30 servings ($2.30 per serving), Novos positions itself as a premium longevity option with a multi-ingredient formula targeting aging. While not the most affordable, its price may be justified for people seeking comprehensive, science-backed support for cellular aging.
In comparison, Life Extension's Creatine & Acetyl-L-Carnitine Energy Plus costs $24.75 for 30 servings ($0.83 per serving). Focusing on energy and cognitive health, it offers good value for everyday use at a lower price point.
Qualia's Senolytic formula, priced at $79 for 12 capsules ($6.58 per serving), is intended for occasional use targeting senescent cells. Its high cost may be reasonable for people specifically looking for advanced anti-aging strategies, but it is less budget-friendly for regular use.
Novos offers a premium formula, but Life Extension provides better value for everyday supplementation, while Qualia's price is higher for a more niche, targeted use.
Novos claims to follow scientific research, offering targeted options to aid in healthy biological aging. You also get access to tools like the Novos Life App to monitor your biological age and lifestyle habits over time.
With transparent ingredient sourcing, third-party testing, and support for HSA/FSA payments, Novos claims to support better accessibility.
However, Novos' return policy is somewhat restrictive, with higher restocking and shipping fees, which could make trial purchases a bit risky. Additionally, with its premium pricing, the brand might not be the most accessible for everyone, particularly if you're unsure about long-term use. While Novos products are generally safe, some people might experience occasional digestive discomfort or headaches when first using the supplements. Make sure to evaluate all the shared points in this article before making any decision.
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