Home » Xyon Review: How Practical Are Its Subscription Based Offerings?

Xyon Review: How Practical Are Its Subscription Based Offerings?

Xyon Review

Xyon is an online telehealth platform that offers haircare support by providing access to virtual consultations with licensed clinicians, prescription approvals, home delivery of medications, and ongoing support from the care team.

Beyond haircare, the platform also focuses on supporting male sexual wellness needs, offering support in tackling concerns like premature ejaculation or weak erections. However, can the platform’s digital-first model tackle haircare and sexual wellness concerns effectively?

In this review, we look at how the brand’s telehealth process works, ranging from onboarding and consultations to prescriptions and home delivery. The review also explores the range of offerings provided, associated brand advantages, and potential limitations.

About Xyon

As per its official website, Xyon is created by licensed clinicians specializing in hair restoration and sexual health. The brand’s direction is shaped by founders Dr Victor Hasson, a hair restoration surgeon and creator of the SiloxysSystem delivery technology, and Dr Simon Pimstone, a licensed physician and drug developer.

To access the platform’s services, you are required to complete a quick online intake form that asks questions about your fitness history, goals, and tolerance to medications. Then, submitted responses are reviewed by a licensed clinician, who may determine if a prescription is appropriate for your needs. Post-approval, your prescriptions are prepared by licensed compounding pharmacies and delivered to your specified address.

As part of its prescription-based haircare offerings, the platform may provide options such as Finasteride with SiloxysSystem gel, Finasteride and Minoxidil with SiloxysSystem gel, Minoxidil/Finasteride tablets, or Dutasteride with SiloxysSystem gel. It also provides non-prescription offerings like the Performance DHT blocking shampoo and Defend Hair & Scalp Serum. At the discretion of licensed clinicians, the platform may also provide access to Generic Viagra (Sildenafil) and Generic Cialis (Tadalafil) to support sexual wellness.

Xyon Review

Xyon Offerings

  1. Hair Care

    The platform’s Hair Care range intends to offer support for common haircare concerns, including pattern hair loss, thinning hair, crowning, and receding hairline. As part of its prescription-based haircare offerings, the platform could provide access to Finasteride with SiloxysSystem gel, Finasteride combined with Minoxidil in SiloxysSystem gel, Dutasteride with SiloxysSystem gel, and Finasteride and Minoxidil Solution. Beyond topical options, it also provides oral medications such as Minoxidil and Finasteride tablets.

    Finasteride could influence the conversion of testosterone into dihydrotestosterone by suppressing the release of the 5-alpha reductase enzyme. It may help lower DHT levels around the follicles, thereby supporting hair growth and slowing miniaturization. Research suggests that Minoxidil works by influencing potassium channel activity in follicle cells, which may support blood flow, prolong the growth phase of the Hair cycle, and encourage thicker strand formation.

    As per its official website, the use of SiloxysSystem gel technology in the topical products is a central feature of the Hair Care range. The system could form a mesh-like barrier on the scalp where it is applied, helping keep the medication at the surface rather than allowing excess absorption into the bloodstream. The gel also avoids propylene glycol and ethanol, which are common irritants, creating a gentler experience for the scalp.

    Non-prescription options within the range include a Performance DHT-Blocking Shampoo, a DHT-Blocking Conditioner, and a Defend Hair and Scalp Serum. These formulas may support surface scalp health and may help maintain a balanced environment around the follicles.

  2. Sexual Health

    Xyon claims to tackle concerns around male sexual wellness, including performance concerns, weak erections, or difficulty in arousal, with the help of its sexual health range. A licensed physician reviews your history and sexual concerns, who may provide prescriptions for compounded ED medications if necessary.

    The Sexual Health range provides access to Generic Viagra (Sildenafil) and Generic Cialis (Tadalafil) tablets. Both these medications belong to the phosphodiesterase type 5 inhibitor class, a group of medications that help boost blood flow to the erectile tissue.

    Sildenafil works by inhibiting the PDE5 enzyme in the smooth muscle of penile blood vessels, reducing the breakdown of cyclic guanosine monophosphate (cGMP). Such effects help activate a protein called cGMP-dependent protein kinase, which reduces calcium levels in the muscle cells, excretes potassium, and deactivates the myosin light chain kinase enzyme. These effects may support relaxation of the penile blood vessels, allowing more blood to flow into the penis.

    Tadalafil is believed to have a longer half-life, with its effects typically lasting for up to 36 hours. This may provide greater flexibility by maintaining PDE5 inhibition over a longer period, which might support more spontaneous sexual activity.

Xyon Advantages

  1. Physician-Led Brand

    Xyon highlights a clinical framework supported by physicians such as Dr. Victor Hasson, MD, known for his work in hair restoration and male pattern hair loss. Dr. Christina Han (MD FRCPC) adds dermatology and clinical care experience that may help guide the platform’s assessment process and condition management recommendations.

    Also, Dr. Simon Pimstone (MD, PhD) guides research leadership that informs the development of Xyon’s prescription formulas and overall clinical model. The brand positions hair thinning and male pattern hair loss as linked to hormonal activity and follicular changes in the scalp. The platform claims that these issues require proper clinical evaluation and management rather than relying only on cosmetic approaches or general retail products.

  2. Follows Digital Health Model

    Xyon follows a digital-first care model by structuring its service around medical steps that resemble what occurs in a dermatology clinic, but delivered through an online platform. The platform’s model includes screening questions, suitability checks, risk assessment, and prescription review before a plan is approved.

    The platform continues this approach after a program is implemented. You receive follow-up support through digital communication with physicians who review progress, adjust medications, and answer medical questions as needed. The platform also provides educational content explaining the science of hair loss and how prescription plans work, which supports the idea that decisions are guided by clinical reasoning.

Xyon Limitations

  1. Narrow Market Positioning

    Xyon’s offerings primarily target DHT-driven hair thinning and follicle preservation rather than everyday cosmetic haircare. For instance, its Performance DHT-Blocking Shampoo uses saw palmetto and rosemary oil to suppress DHT production and promote follicle health while cleansing without stripping moisture. The brand’s Defend Hair & Scalp Serum employs a biphasic formula to block DHT, strengthen hair anchoring, and boost microcirculation, focusing on scalp and follicle support.

    Such emphasis on androgen pathways and follicle miniaturization creates a robust clinical identity, although the brand’s range of supporting conditioners, hair oils, and everyday hair/scalp care options for hydration appears limited. Its lineup centers on DHT-focused haircare over broad cosmetic categories like styling or breakage repair.

  2. Minimal Partnerships With Major Retailers

    Xyon primarily sells its non-prescribed products through its own website, with additional availability through select professional clinics and a small number of specialty beauty distributors. There is no visible placement in large national retailers, mainstream pharmacies, or mass online marketplaces, which limits exposure to shoppers who rely on familiar retail environments when choosing hair or wellness products.

    This distribution model aligns with Xyon’s medically oriented offerings in categories such as Hair Care and Sexual Health, which are designed to support hormone-related concerns and often require more specialized handling. However, this approach also restricts access for consumers who prefer to purchase products in widely recognized retail settings or who expect to discover clinical-grade brands alongside other premium haircare or wellness options.

  3. Subscription-Based Approach

    Xyon relies strongly on a subscription-based model, which might limit flexibility. Its prescription products are offered almost exclusively through recurring 90-day cycles that renew automatically. This structure means you are left to stay enrolled in the subscription system to receive ongoing care, and prescription items are not refundable once processed.

    As there is no short-term or one-time purchase option for prescription options, you are required to commit to a continuing program to access the medications. This may also reduce control if you prefer to manage refills on your own timeline or want the option to pause, delay, or purchase offerings only when needed.

Pros

  • The brand offers a range of prescription and non-prescription haircare offerings, including topical Minoxidil, Finasteride tablets, and DHT-Blocking Shampoo.
  • Emphasizes the use of a patented SiloxysSystem gel in topical offerings to improve the topical delivery of ingredients.
  • Licensed physicians review your conditions and oversee programs, lending medical credibility.
  • The brand offers discreet home delivery of medications with free shipping.

Cons

  • A few users have noted that the brand's offerings, such as topical Finasteride, have a premium price.
  • Lack of insurance coverage may lead to added medical costs.

Xyon Alternative Brands

  1. Rogaine

    When comparing the brands, both Rogaine and Xyon function within the haircare support segment. However, the brands take fundamentally different approaches to care models, technological integration, range of offerings, accessibility, and service ecosystem.

    Rogaine positions itself as an over-the-counter brand that helps address hair loss through extensive research on Minoxidil. Meanwhile, Xyon frames its identity around clinician-led prescription care, advanced delivery systems, and precision dosing.

    Rogaine’s product range centers entirely on Topical Minoxidil delivered through Foam and Solution formats for both men and women. As per its official site, the Minoxidil-based offerings from the brand are supported by Tricho-Prime Technology, which intends to prepare the scalp for hair regrowth. Some core offerings from the brand include the Men’s Foam, Men’s Thickening 2-in-1 Shampoo + Conditioner, Women’s Foam, and Women’s Solution (2% Minoxidil).

    On the other hand, Xyon presents a broader, prescription-based catalog anchored by the SiloxysSystem™ gel, which localizes Finasteride, Dutasteride, Minoxidil, or Combination topical options directly to the scalp to maximize follicular exposure while minimizing systemic absorption. It is important to note that these prescription offerings are made available only after completing online assessments and approval from licensed clinicians.

    As part of its Women’s haircare range, the platform may provide offerings like Minoxidil Tablets, Topical Finasteride and Minoxidil for Women, and Spironolactone tablets. The platform also provides access to prescriptions for Generic variants of Cialis (Tadalafil) and Viagra (Sildenafil) to support male sexual wellness.

    Rogaine maintains accessibility through its over-the-counter availability, gender-specific packaging, online quizzes, and a digital education ecosystem that explains hair-loss mechanisms and long-term maintenance. Meanwhile, Xyon operates through online consultations reviewed by licensed clinicians, followed by discreet shipping and order management through a digital dashboard.

  2. Nutrafol

    Nutrafol maintains a niche in the haircare space, offering multiple formulations to tackle concerns like hair shedding, weak strands, and thinning. The brand’s philosophy is centered around the view that interconnected factors, including hormonal fluctuations, metabolic changes, stress levels, nutritional gaps, and age-related shifts shape hair thinning.

    Such philosophy guides the brand’s product lineup, which is organized around targeted nutraceutical formulations across women, men, and skin categories. Nutrafol Men is the brand’s core product that is formulated to help you address issues such as thinning hair, hair fall, or dandruff. Alongside the capsule-based offering, the brand extends its approach by pairing the product with offerings like Collagen Builder, DHT Inhibitor, and Hair Serum.

    The brand also maintains a distinct women’s category range, which provides offerings such as Women’s Vegan, Women’s Balance, and Postpartum. Such offerings are positioned to align with varying hormonal and nutritional needs. As part of its skincare lineup, the brand also offers the Clear Skin Nutraceutical, which intends to support a radiant complexion while lowering the risk of concerns like breakouts and redness.

    On the other hand, Xyon follows a more clinically structured path through dermatologist-guided prescription care. A major component of the platform is the use of its patented SiloxysSystem gel, which helps the topical medications remain localized to the scalp and decrease systemic absorption.

    The platform’s offerings are rooted in prescription-grade and compounded formulations rather than supplement-based options. As part of its men’s haircare range, the platform could provide access to Topical Finasteride with SiloxysSystem Gel, Finasteride & Minoxidil Solution, Dutasteride with SiloxysSystem Gel, and non-prescription offerings like Performance DHT-Blocking Conditioner and the Defend Hair & Scalp Serum.

    Xyon also maintains a separate lineup for women’s haircare needs that mirrors its clinical orientation. Some offerings under this lineup include the Topical Finasteride and Minoxidil Solution, Minoxidil Tablets, and Spironolactone Tablets.

How Did We Evaluate Xyon?

  1. Real Consumer Reviews

    In evaluating the brand, we looked at the verified user feedback available across Reddit threads and discussions between 2024 and 2025. Xyon appears on Reddit mostly in the context of topical finasteride and dutasteride for managing hair loss, with users sharing both side-effect concerns and success stories.

    One user who used the topical dutasteride and minoxidil+finasteride combinations from the brand shared positive experiences, describing no observable side effects and incremental improvement in hair density and volume.

    Another Reddit thread indicated that one user who tried the topical minoxidil + finasteride solution (6% minoxidil, 0.25% finasteride) for six months experienced reduced shedding and visible improvements around month five. However, the user mentioned experiencing an itchy scalp from minoxidil in the formula.

    Such Reddit feedback and discussions indicate that the brand’s topical offerings provided visible hair benefits, such as improved density and reduced shedding for some consumers. However, concerns around sexual side effects and itching suggest that individual responses to the brand’s products may vary.

  2. Brand Reputation

    To evaluate Xyon’s brand reputation, we examined its background and ratings across independent review forums.

    On TenereTeam, the brand maintains a 4.6 out of 5 score based on more than 1,900 reviews. Most users highlighted strengths such as personalized condition management plans, access to specialist physicians through online consultations, and the brand’s use of the patented SiloxysSystem Gel. However, a few users noted that the brand’s programs carried higher price points, especially for topical finasteride formulations. A recurring point of criticism involves the absence of a clear cancellation policy, with customers stating that orders are not subject to cancellation once processed.

    We also found that the brand maintains a minimal to no presence across other independent review platforms, including Better Business Bureau and Trustpilot. The absence of cross-platform reviews could make it difficult to assess long-term performance, customer service responsiveness, and brand reliability across a wider consumer base. As a result, much of our available credibility assessment relies heavily on a single review source.

Frequently Asked Questions

  • Does Xyon offer personalized dosing based on pharmacokinetic testing?
    No. Licensed clinicians at the platform typically take dosing decisions based on symptom history, pattern severity, and tolerability of medications. They do not make decisions on the basis of serum finasteride levels, DHT measurements, or metabolic profiling.
  • Can Xyon identify fungal scalp infections remotely?
    No. The platform is not equipped to identify fungal scalp infections remotely, as it relies on remote consultation. Fungal scalp infections like tinea capitis typically require physical examination, KOH microscopy, or fungal cultures, which the platform does not provide.

Conclusion

Xyon positions itself as a physician-led platform built around experts in dermatology, hormonal hair loss, and clinical research. Assessment steps, prescription pathways, and program adjustments follow a structure similar to dermatology clinics, which may position the platform’s services under clinician oversight.

However, there are some limitations to consider before opting for the platform’s services. Xyon’s product lineup remains tightly focused on tackling DHT-driven thinning, with its shampoos and topical offerings formulated for follicle preservation rather than broader cosmetic needs like moisture, styling, or breakage repair.

Its subscription-based prescription model might also restrict short-term or one-off purchasing, creating stronger commitment requirements even if you prefer one-time purchases or do not require an extended supply.

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This project was supported in part by NSF Grant IIS-03-25867 (ITR: An Electronic Field Guide: Plant Exploration and Discovery in the 21st Century) and by the Washington Biologists' Field Club.
Any opinions, findings, conclusions or recommendations expressed in this material are those of the authors and do not necessarily reflect the official views, opinions, or policy of the National Science Foundation (NSF).