Developed by Niagen Bioscience, Tru Niagen is centered around the use of nicotinamide riboside (NR). The brand offers NR-based supplements to improve NAD+ levels, which could help support energy levels, DNA repair, and healthy aging.
The offerings from Tru Niagen have undergone 35+ human trials and safety assessments by global health authorities. The brand also offers subscription plans, help desk support, and ongoing education on cellular health through blogs from Tru Niagen Labs.
In this review, we cover everything you need to know about Tru Niagen, including the brand's history, product offerings, advantages, and potential brand limitations. The review also takes a look behind Tru Niagen's research on NAD, and if the brand's offerings can fit into your fitness goals.
Established by ChromaDex (now Niagen Bioscience), Tru Niagen maintains a specialized focus on supporting cellular health through the restoration of NAD+ (nicotinamide adenine dinucleotide) levels. NAD+ is a coenzyme found in bodily cells, which is essential for processes like cellular energy production, gene expression, immunity, and the regulation of aging.
The brand offers a patented form of nicotinamide riboside (NR) (called Niagen®), which acts as a bioavailable precursor to NAD+. The key ingredient in the brand's offerings, Niagen®, is backed by more than 400 peer-reviewed studies, 50+ international patents, and 300+ global research collaborations.
As per Tru Niagen's claims, Niagen® may safely elevate NAD+ levels by up to 150%, depending on dosage and duration. The brand is transparent about its ingredients, avoiding synthetic stimulants, artificial additives, and unnecessary fillers.
Some of the popular offerings from Tru Niagen include the Tru Niagen capsules, which are available in 150mg and 300mg dosages for daily NAD+ support. For convenience, the brand also offers Stick Packs with added prebiotics and the NAD+ Immune Boosting Duo, a curated bundle that supports both immunity and cellular energy.
Tru Niagen 300mg could help support cellular health by increasing NAD+ (nicotinamide adenine dinucleotide) levels. The Tru Niagen 300mg capsules contain Niagen® (nicotinamide riboside chloride), a patented and clinically studied NAD+ precursor.
As per the brand claims, Niagen® is more effective than other NAD+ boosters and may raise NAD+ levels by over 50% with consistent use. It is designed to be easily absorbed and transported across cell membranes to support efficient NAD+ production.
Tru Niagen 300mg may support multiple health aspects, including cellular energy production, brain function, heart health, and muscle function. It is also formulated without allergens and GMOs and is certified Halal and Kosher.
The makers recommend taking one Tru Niagen 300mg capsule daily. The dosage can also be increased to 3 capsules per day based on your needs and guidance from a healthcare provider.
Tru Niagen 150mg could help support healthy NAD+ levels, a molecule your cells need for energy production, repair, and resilience. The 150mg version offers a flexible serving size, with each serving containing two vegetarian capsules to help restore NAD+ levels.
Consistent use of Tru Niagen 150mg may help support bodily functions, including brain health, cardiovascular performance, and muscle recovery. The supplement also undergoes rigorous testing for quality, safety, and potency by independent third-party labs.
Tru Niagen 300mg Stick Packs provide a flavorless drink mix that aims to support your energy levels and healthy aging. Each stick (4g) contains 15 calories, 300mg of Niagen, and 3 g of dietary fiber.
One box includes 30 stick packs and costs $58 for a one-time purchase. If you choose the subscription option, you'll save 20%, bringing the price down to $46.40 and receiving monthly deliveries for uninterrupted support.
Tru Niagen 300mg Stick Packs come with NSF Certification, ensuring that every stick meets strict standards for quality, purity, and safety. The stick packs could be particularly helpful whether you are coping with high physical demands or navigating stress. They may help you stay energized and resilient at the cellular level.
Tru Niagen Pro 1000mg is a high-potency NAD supplement that may help fuel cellular energy, support metabolic function, and aid in DNA repair. By increasing NAD+ levels, Tru Niagen Pro may enhance your cells' ability to produce ATP, the primary source of energy your body needs to function at its best.
As your NAD+ levels naturally decrease with age, the Tru Niagen Pro 1000mg could help support NAD+ levels, which may help support energy, focus, and resilience. Consistent use of the supplement might also help improve focus, boost physical endurance, and reduce post-exercise recovery time.
According to its official site, one jar of Tru Niagen Pro 1000mg is available at a one-time purchase price of $116. If you prefer consistent delivery and added value, a subscription plan is available, which reduces the price to $92.80 per month.
Tru Niagen Immune 150mg aims to strengthen your immune system, especially during times of stress or vulnerability. During times of illness, the body's NAD+ levels may drop and weaken immune resilience. By replenishing NAD+ levels, Tru Niagen's Immune 150mg could help your immune cells function more effectively.
As per its official site, one capsule of Tru Niagen Immune 150mg features 50mcg (2000 IU) of vitamin D3 as VegD3, 180mg of vitamin C, and 30mg of Theracurmin. VegD3 is a plant-based and highly bioavailable form of vitamin D3, which may help activate immune cells and support your body's natural defenses.
Vitamin C in Tru Niagen Immune 150mg acts as a potent antioxidant, which could protect your immune cells from oxidative stress. Zinc gluconate and citrate are also included in the formulation, which may help support tissue repair and help your body defend against infections more effectively.
The Tru Niagen® NAD+ Immune Boosting Duo includes one unit each of the Tru Niagen® Immune and Tru Niagen® 300 mg supplements. The duo aims to support energy metabolism, immune resilience, and long-term vitality.
Tru Niagen Immune features a mix of immune-boosting compounds like zinc, vitamin C, and vitamin D3. These ingredients may help protect immune cells from oxidative damage, regulate immune responses, and aid in wound healing.
Meanwhile, the Tru Niagen® 300 mg in the NAD+ Immune Boosting Duo focuses on raising the body's NAD+ levels, which may help support cellular energy metabolism, DNA repair, and vitality.
As per its official site, the Tru Niagen® NAD+ Immune Boosting Duo is available at a one-time purchase price of $85. Opting for a subscription will further lower the price to $68.
Tru Niagen operates under its parent company, Niagen Bioscience (formerly ChromaDex), which is built on a foundation of scientific rigor and innovation. Since its establishment in 1999, ChromaDex has been at the forefront of cellular health, collaborating with over 275 global scientific research initiatives. With 38 peer-reviewed human clinical trials confirming Niagen®'s safety and effectiveness in boosting NAD+ levels, the Tru Niagen brand has maintained scientific credibility and a strong brand image.
Tru Niagen maintains a commitment to quality and transparency. Every batch of the Tru Niagen formulations undergoes a comprehensive series of 22 internal and third-party tests, aiming to ensure potency, purity, and label accuracy. The brand uses ISO/IEC 17025:2017-accredited labs to ensure scientifically validated quality.
Moreover, third-party independent certifiers like NSF, Alkemist Labs, Star-K (Kosher), and IFANCA (Halal) frequently inspect and audit all the manufacturing facilities of Tru Niagen. To offer an added layer of transparency, Tru Niagen also provides consumers with access to a Certificate of Analysis (COA) to verify the findings of the lab testing results.
Beyond manufacturing, Tru Niagen has made efforts to build trust through consumer education and open communication. The brand provides its customers access to science-backed health insights through editorial blogs (Tru Niagen Labs), a user-friendly quiz for personalized recommendations, and rewards (such as $30) for every referral made to a friend.
Tru Niagen functions in global NAD+ science through its ChromaDex External Research Program (CERP®). With over 275 collaborations in more than 30 countries, the CERP program supports independent, investigator-led studies by supplying pharmaceutical-grade Niagen® and expert technical resources. These resources help advance research in healthy aging, cellular metabolism, and mitochondrial function.
Niagen® by Niagen Bioscience is the most extensively studied nicotinamide riboside available. It is also the only patented NRCl formulation with global regulatory recognition, including approvals from the FDA (NDI, GRAS), EFSA, Health Canada, and Australian TGA.
More than 95% of CERP® studies are investigator-initiated and third-party funded, reflecting the credibility and independence of the research. Tru Niagen's scientific leadership has earned multiple industry awards, including NutraIngredients EU's 2024 Healthy Aging Ingredient of the Year and Nutritional Outlook's 2019 Best Ingredient Supplier awards.
Tru Niagen's offerings come with a higher price tag, possibly due to the brand's extensive scientific research and investment in research and development. For instance, one bottle of Tru Niagen Pro 1000mg costs $116, which only lasts a month's supply. The high price point of Tru Niagen's formulations may limit their accessibility, especially to consumers seeking budget-friendly NAD+ supplements.
All offerings from Tru Niagen primarily contain nicotinamide riboside chloride (NRCl) as a signature ingredient. While the ingredient has undergone extensive studies and has been proven to raise NAD+ levels, the Tru Niagen brand lacks the broader blend of ingredients that some competitors offer.
Many NAD+ supplements from brands like Thorne contain added compounds like NMN, CoQ10, or resveratrol to support anti-aging benefits and vitality further. The limited ingredient approach of Tru Niagen might not appeal to consumers seeking a more comprehensive product with additional benefits.
The NAD+ supplements from Tru Niagen are typically well-tolerated by consumers. However, some users may experience side effects when taking Tru Niagen formulations. These may include altered cellular metabolism, digestive discomfort, fatigue, headache, nausea, flushing, cramps, etc. The brand's formulations may not be suitable for everyone, particularly for consumers with sensitivities to metabolic or cellular-activating compounds like NAD.
To evaluate Tru Niagen, we analyzed the customer response to the brand's offerings across platforms like Amazon.
For instance, most Amazon consumers who tried the Tru Niagen 300mg observed noticeable reductions in fatigue, brain fog, and signs of age-related decline. Many users also experienced benefits like increased energy, clearer thinking, and improved mood after consistent use of Tru Niagen 300mg. However, a few consumers experienced headaches and digestive discomfort.
Similarly, Tru Niagen Immune 150mg was well-received by Amazon consumers, particularly for its immune-supporting and cognitive benefits. Many users shared that they experienced fewer and milder colds after taking the supplement regularly. Some users even experienced benefits like improved memory and sleep quality. However, a few consumers remain dissatisfied with the product's premium pricing and packaging quality.
As part of our evaluation of Tru Niagen, brand credibility was a major factor. We assessed Tru Niagen's history, scientific backing, certifications, and consumer reputation across review platforms like Trustpilot and Better Business Bureau.
Tru Niagen is developed by Niagen Biosciences (formerly ChromaDex), a company rooted in over 20 years of NAD+ research. We also considered the fact that the offerings from Tru Niagen have received endorsements from leading researchers, such as Dr. Charles Brenner and Dr. Roger Kornberg, adding more credibility to the brand.
On Trustpilot, the profile of Tru Niagen remains unclaimed, indicating a limited presence on the Trustpilot platform. Tru Niagen is not accredited by the Better Business Bureau (BBB) website and has received eight complaints, with an “A-” rating on BBB.
Both Life Extension and Tru Niagen brands focus on developing research-backed formulations to promote health and longevity. However, the brands differ in their approach, product offerings, and primary focus areas.
Life Extension is a well-established brand that has been operating since 1981 in the supplement industry. The brand offers more than 400 vitamins and supplements across 40+ health categories, targeting benefits like anti-aging, immune support, heart health, joint care, cognitive function, etc.
Tru Niagen specifically targets the replenishment of NAD+ (nicotinamide adenine dinucleotide) levels, a coenzyme crucial for cellular energy production and repair. With over 35 human clinical studies supporting its claims, Tru Niagen emphasizes its scientific backing, with over 400 published studies on Niagen®.
Both brands are committed to scientific rigor, but Tru Niagen's approach to NAD+ science is backed by its unique patent and over 25 years of clinical research, specifically on NAD+ boosters.
Meanwhile, Life Extension offers a broad spectrum of supplements across various health domains while also providing access to 250+ lab tests and virtual consultations. These offerings may appeal to consumers looking for a comprehensive wellness routine.
There are also slight price differences between similar products from both brands. For instance, one jar of Life Extension's NAD+ Cell Generator 300mg costs $40.50, which contains 30 capsules. In contrast, one jar of Tru Niagen 300 costs $49, also providing 30 capsules per bottle.
Thorne and Tru Niagen (Niagen Bioscience) are both reputable brands offering premium health supplements. However, the brands differ significantly in their focus, product offerings, pricing, and return policies.
Thorne is known for its wide range of products targeting various health aspects, including sports performance, immune support, sleep, stress management, and vitality. Thorne's product lineup includes supplements like Daily Electrolytes for hydration, Creatine Monohydrate for muscle recovery, and Resveracel to support NAD+ production.
On the other hand, Tru Niagen is a more specialized brand focusing on optimizing cellular health by boosting NAD+ (nicotinamide adenine dinucleotide) levels. All offerings from Tru Niagen, such as its Tru Niagen 300mg or Tru Niagen Pro, contain the signature ingredient called Niagen®. It is a patented and enhanced variant of vitamin B3 that holds the ability to increase the body's natural NAD+ levels, contributing to cellular health and longevity.
When it comes to pricing, Thorne's products generally fall within a moderate to higher price range. For example, one bottle of Basic Nutrients 2/Day (a multivitamin) is priced at $34 for a two-month supply. One bottle (60 capsules) of Thorne's ResveraCel costs $58.
However, due to the specialized nature of its offerings, Tru Niagen tends to have premium pricing. For example, one bottle of Tru Niagen Pro 1000mg costs $116 and lasts a 30-day supply. Also, one jar of Tru Niagen's Immune 150mg, which aims to support immunity and antioxidant defense, is priced at $41.
Both Tru Niagen and Thorne brands offer subscription services to make regular purchases more convenient and affordable. Thorne provides a 10% discount on recurring orders for subscribers and a 20% discount on subscriptions to 3 or more Thorne products. Tru Niagen offers a 20% discount and free shipping for its subscription service.
Tru Niagen is based on cellular health science, with a clear and consistent focus on NAD+ replenishment through its patented form of nicotinamide riboside (Niagen®). The brand is built on over 25 years of extensive scientific research on NAD and offers NAD+ formulations in different strengths to cater to multiple health needs.
The Tru Niagen brand also gives access to health blogs, referral rewards, and an online Help Desk for addressing queries. It also maintains a professional website and offers online educational resources to support user understanding.
That said, Tru Niagen does have some limitations. The offerings from Tru Niagen focus on just one core ingredient, Niagen, while other brands like Thorne include added compounds like zinc and resveratrol for broader fitness support.
Moreover, some consumers may experience side effects with NAD supplements of Tru Niagen. These could manifest as symptoms like nausea, stomach discomfort, headaches, cramps, and dizziness.
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