Home » Joi + Blokes: Personalized Hormone Care or Telehealth Overreach?

Joi + Blokes: Personalized Hormone Care or Telehealth Overreach?

Joi + Blokes Review

Joi + Blokes is a telehealth brand that provides personalized hormone and wellness care. The company addresses concerns such as testosterone optimization, energy, performance, and longevity, as well as perimenopause, menopause, and hormone balance.

Its services include comprehensive lab testing, in-depth consultations, and customized plans aimed at meeting individual needs rather than relying on standardized solutions.

Its available therapies include testosterone replacement for men, estrogen and progesterone options for women, thyroid care, peptides, and GLP-1 weight management medications.

In this review, we will explore the Joi + Blokes' strengths, potential limitations, and how its offerings compare within the wellness market. We will also evaluate the consumer responses to understand brand credibility.

About Joi + Blokes

Joi + Blokes claims to provide personalized, diagnostics-first care for hormone health, longevity, and preventive wellness.

Founded by Josh and Katy Whalen, the brand aims to support hormone optimization, performance, sexual health, metabolic wellness, and support for those facing hormonal changes such as perimenopause and menopause.

According to its official website, Joi + Blokes's services span several categories, including hormone therapies such as testosterone replacement therapy, enclomiphene, hormone replacement therapy, and thyroid care.

It also offers weight management procedures like GLP-1 medications, sexual health options including oxytocin nasal sprays and the vFit® Gold+ device, and longevity-focused options such as NAD+, Sermorelin, B12 + MIC injections, glutathione, and rapamycin.

The brand's diagnostic services range from hormone panels and food sensitivity testing to advanced lab assessments.

Joi + Blokes also offers “Smart Supplements” designed for hormone balance, energy, sleep, gut health, and hair support, along with skin care products such as peptide-based creams. Joi + Blokes provides its services through a telemedicine model that combines advanced laboratory testing, licensed clinician oversight, and one-on-one coaching.

Joi + Blokes Review

Joi + Blokes Offerings

  1. Joi + Blokes Testosterone Replacement Therapy

    Joi + Blokes provides a Testosterone Replacement Therapy (TRT) program to address low testosterone levels. The program follows a diagnostics-first process, beginning with a medical evaluation by a licensed, board-certified clinician. TRT is only prescribed after this review and is not intended for performance enhancement in men with normal testosterone levels.

    The program uses testosterone cypionate, supplied via prescription and delivered directly to the person's address. Plans include quarterly lab tests to monitor testosterone and other relevant health markers. Clinicians adjust dosing based on lab results and ongoing assessments.

    Low testosterone could be related to factors such as stress, injury, weight gain, illness, or prior testosterone misuse. Potential signs that may prompt evaluation include fatigue, decreased libido, and reduced concentration.

  2. Joi + Blokes Levels

    Joi + Blokes Levels may support hormonal balance, metabolism, recovery, and immune function through a blend of botanicals and nutrients. It includes pine bark extract, sourced from the bark of maritime pine trees, which is rich in polyphenols and antioxidants that might help combat oxidative stress.

    As per the official website, Levels could support cardiovascular health, promote nitric oxide production, and improve blood flow, which may have implications for endurance, recovery, and sexual function.

    Tongkat Ali (Eurycoma longifolia) in this formula may help maintain healthy testosterone levels, support libido, and contribute to hormonal balance, potentially aiding energy, mood, and overall physical performance.

    Additional ingredients present in Levels include DHEA and fenugreek extract, which the brand states may support testosterone synthesis and metabolic processes.

    For stress management and mental clarity, Levels contains KSM-66® Ashwagandha root extract, which may help the body modulate stress responses and L-DOPA that might aid in mood regulation.

    Levels also has anti-inflammatory and antioxidant compounds, such as turmeric root extract (with curcuminoids) and alpha-lipoic acid, which might support immune function, recovery, and long-term health. Diindolylmethane (DIM) may help balance estrogen metabolism, while boron is included for hormone balance and bone health.

    Levels is formulated with vitamin D3, vitamin K, riboflavin (B2), B6, and B12, which may provide metabolic support and energy production.

  3. Joi + Blokes NAD+

    Joi + Blokes gives access to NAD+ (nicotinamide adenine dinucleotide) supplementation, which is a coenzyme found in all human cells and is involved in metabolic processes such as converting nutrients into energy, supporting DNA repair, and maintaining cellular function.

    Research indicates that NAD+ levels decrease with age. Lower levels can cause reduced cellular energy production, diminished DNA repair capacity, and elevated oxidative stress. NAD+ is involved in mitochondrial function, DNA repair pathways, neuronal signaling, and other biochemical processes related to metabolism and cellular maintenance. It may also help with immune regulation, liver function, and oxidative stress response.

  4. Joi + Blokes Enclomiphene

    Joi + Blokes provides Enclomiphene in the form of a daily oral capsule intended to increase the body's natural testosterone production. Enclomiphene is known as a selective estrogen receptor modulator (SERM) that works on estrogen receptors in the hypothalamus. It could help reduce negative feedback on the hypothalamic-pituitary-gonadal (HPG) axis by blocking estrogen signaling in this area.

    This action leads to increased release of gonadotropin-releasing hormone (GnRH), which may stimulate the pituitary gland to make luteinizing hormone and follicle-stimulating hormone. LH prompts the testes to produce testosterone, while FSH supports sperm production.

  5. Joi + Blokes Hormones (BHRT)

    Joi + Blokes offers Bioidentical Hormone Replacement Therapy (BHRT) for both men and women, designed to address hormone deficiencies or imbalances identified through clinical evaluation and lab testing. Bioidentical hormones are chemically similar to those hormones naturally produced by the body, which can make them more compatible and effective in supporting the body's hormonal needs.

    BHRT from Joi + Blokes might help in restoring hormonal balance, potentially elevating mood and libido by maintaining healthy testosterone levels, enhancing energy, and supporting sexual wellness. It might also help in supporting mental health by addressing symptoms such as depression, anxiety, and mental fog. In the long term, BHRT is believed to help preserve muscle mass, bone density, and metabolic function, supporting healthy aging.

    Bioidentical Hormone Replacement Therapy Plans include testosterone, estrogen, progesterone, or a combination of hormones, depending on the person's needs. Testosterone therapy, available as a cream or an injection, plays a critical role in maintaining optimal muscle mass, bone density, and libido. Systemic estrogen, offered in capsule, cream, or patch form, supports heart, brain, and bone health while helping to regulate stress. Vaginal estrogen, available as a cream or suppository, might help relieve symptoms of vaginal atrophy such as dryness, itching, and discomfort during intercourse. Progesterone, which balances the estrogen effects and influences mood and sleep, is available as a capsule or cream.

  6. Joi + Blokes Balance

    As per the official website, Joi + Blokes Balance may support hormone regulation, metabolism, stress response, and immune function. It combines DIM (diindolylmethane), which could help promote healthy estrogen metabolism that might help maintain hormonal balance.

    Joi + Blokes Balance also has magnesium and zinc, which may support thyroid function, hormone activity, energy metabolism, and cardiovascular health, while reishi mushroom, an adaptogen, could help modulate the body's response to stress and support immune function. Turmeric, rich in curcumin, and selenium in the formula contribute to inflammatory regulation and support thyroid-related pathways.

    Joi + Blokes Balance also combines amino acids l-arginine and l-carnitine, which play important roles in nitric oxide production, blood flow, and cellular energy metabolism. Biotin is included to support healthy hair, skin, and nails.

  7. Joi + Blokes (!) Scream Cream

    Scream Cream by Joi + Blokes may support sexual wellness by enhancing local circulation, sensitivity, and natural arousal responses in women. It includes Sildenafil 2%, Theophylline 3%, Pentoxifylline 2%, and L-Arginine 6%, which work together to promote vascular function and blood flow.

    L-Arginine in this cream could support nitric oxide production, encouraging vasodilation and improved circulation in targeted areas. Sildenafil in Scream Cream may help increase tissue responsiveness, while theophylline and pentoxifylline could support vascular function and tissue oxygenation. The makers state that Scream Cream may support physiological responses related to arousal, lubrication, and sensitivity.

  8. Joi + Blokes Sermorelin

    Joi + Blokes offers Sermorelin as a peptide therapy aimed at supporting the body's natural growth hormone production. Sermorelin works by mimicking the body's growth hormone–releasing signals, prompting the pituitary gland to produce human growth hormone (HGH). As growth hormone levels naturally decrease with age, this can affect muscle mass, fat distribution, energy, skin elasticity, and bone health.

    Sermorelin may support muscle tone, body composition, cellular repair, and metabolic function by stimulating the body's endogenous growth hormone pathways. This therapy could also have a positive impact on sleep quality, post-exercise recovery, and energy levels. As a peptide, a short chain of amino acids, Sermorelin interacts with the endocrine system to help maintain key physiological processes.

Joi + Blokes Advantages

  1. Specialized Clinical Oversight

    Joi + Blokes claims to work with a clinical advisory team that includes physicians, nurses, pharmacists, and researchers specializing in hormone health, longevity, menopause, and metabolic optimization. Its members include Dr. Melissa Loseke, Ben Bikman, Brooke Estes, and Jocelyn Freimuth. This means every recommendation, whether it's advanced hormone therapy, supplement support, or lifestyle guidance, is grounded in expert clinical judgment, not automated protocols or one-size-fits-all plans. These virtual consultations with licensed clinicians who review the lab results can help track progress and make adjustments to keep the plan aligned with any health changes. This ensures a more precise, responsive, and safe approach to managing hormone balance and long-term wellness.

  2. Comprehensive Lab Testing

    Joi + Blokes provides diagnostic panels that measure a wide range of health markers. The Comprehensive Panel evaluates 110 biomarkers across multiple areas, including metabolism, cardiovascular function, hormone levels, bone and muscle condition, kidney and liver health, inflammation, thyroid activity, oxygen transfer, and cognition. This approach allows for the assessment of several physiological systems in a single test.

    The Complete Hormone Panel by Joi + Blokes measures 56 hormone-related biomarkers associated with energy regulation, weight management, and mood. Testing is available as a single assessment or can be scheduled on a bi-annual or quarterly basis for continued monitoring.

    Each panel includes a 60-minute consultation with a board-certified clinician to review results and determine next steps. These may involve adjustments to lifestyle habits, nutrition, or prescribed plans. Blood samples can be collected at LabCorp or Quest locations, or, in select states, through a mobile phlebotomy service for an additional $99. Ongoing support is available through health coaching, direct messaging with the care team, and progress tracking over time. This continued support is available through health coaching, direct messaging with the care team, and regular progress tracking, helping the user stay informed and engaged in their health management.

Joi + Blokes Limitation

  1. Insurance Coverage Restrictions

    Joi + Blokes does not bill insurance directly for most services, plans, or lab tests, as many of their preventative and advanced care options are not typically covered. While the brand assists with prior authorizations and prescription submissions, people must confirm coverage and manage reimbursements independently. Insurance eligibility is generally limited to traditional, FDA-approved medications, such as estrogen, progesterone, thyroid prescriptions, and certain GLP-1/GIP drugs for weight management or type 2 diabetes, including Ozempic, Wegovy, Zepbound, and Mounjaro, which may be covered if filled at a local pharmacy. This limitation could result in higher out-of-pocket costs unless an individual's plan covers the specific medications required. HSA or FSA funds may be used for eligible expenses, and Joi + Blokes provides receipts and a Letter of Medical Necessity to support reimbursement requests. However, since coverage and approval vary by plan, people may need to plan for upfront payments and verify benefit eligibility in advance to avoid unexpected expenses.

Pros

  • Offers personalized hormone care separately for women and men.
  • Features advanced lab panels covering up to 110 biomarkers.
  • Provides clinician appointments, with durations of 30–60 minutes depending on panel.

Cons

  • Not all services may be covered by insurance, potentially leading to out-of-pocket expenses.
  • Exclusively online consultations may not suit people who prefer face-to-face expert interactions.

Joi + Blokes Alternatives

  1. Hone Health

    Hone Health focuses primarily on identifying and managing testosterone deficiency through medical therapy, keeping its scope centered on symptom relief rather than broad wellness optimization. Its procedure options include injectable testosterone, topical formulations, and sublingual troches, along with medications such as clomiphene citrate and anastrozole. While Hone also offers support for weight, thyroid, and sexual health, these services are secondary to its core TRT programs.

    As per its official website, Hone Health handles its lab work through at-home test kits analyzed by CLIA- and CAP-certified facilities, targeting testosterone and closely related markers. This narrower testing panel is designed for efficiency and is paired with virtual consultations conducted asynchronously by licensed physicians, often with backgrounds in endocrinology or internal medicine. Hone Health's pricing range remains on the lower end, with laboratory testing around $60 and monthly plans generally ranging from $20 to $60.

    Joi + Blokes, on the other hand, takes a wider-reaching approach, blending testosterone therapy with programs for hormone balance, metabolic health, sexual function, and longevity. Its plan menu includes testosterone cypionate injections, enclomiphene, various peptides, oxytocin spray, and weight management prescriptions such as Zepbound. The diagnostic process covers far more ground, with tiered lab panels assessing between 56 and 110 biomarkers to create an in-depth profile of hormonal and overall health.

    According to Joi + Blokes's official website, Blood samples can be collected at home or processed through partner laboratories like LabCorp and Quest Diagnostics. Clinical guidance is more comprehensive, with care plans shaped by both broad lab data and symptom patterns.

    The brand's pricing range begins at $149 per month and increases with advanced diagnostics and more suited routines. Joi + Blokes claims to be a holistic hormone and wellness provider rather than a strictly TRT-focused service by extending into weight management, sexual health, and targeted longevity protocols.

  2. Maximus Tribe

    As per its official website, Maximus Tribe operates on a narrowly defined hormone optimization model centered around boosting natural testosterone production without suppressing the hypothalamic-pituitary-gonadal axis. Its core EP Protocol combines enclomiphene citrate with pregnenolone to enhance endogenous testosterone while maintaining fertility. The program is structured as a single fixed-dose protocol (typically 6.25 mg–12.5 mg enclomiphene) under medical supervision.

    Maximus Tribe gives access to lab testing conducted at home, tracking key markers such as total and free testosterone, estradiol, and SHBG, at a flat rate of $99.99 per test. The subscription itself costs $99.99/month, and onboarding is completed within 48 hours entirely through a digital platform. However, supplement availability is minimal, limited to optional add-ons like the “Building Blocks” multivitamin. Maximus does not offer TRT, peptides, a sexual health plan, or longevity-focused supplements, and its scope is intentionally limited to consistent, non-suppressive testosterone enhancement for performance-related goals like energy, focus, and drive.

    On the other hand, Joi + Blokes offers a much wider range of hormone and wellness services, including TRT, enclomiphene-based protocols, peptide therapies, weight management drugs such as Zepbound, sexual health options like oxytocin spray, and supplements like Levels, Focus, and Hair Support. Its diagnostic options include tiered lab panels covering 56–110 biomarkers, with pricing starting at $149/month and increasing for more advanced testing or therapies.

    The main difference is in their scope and protocol structure, as Maximus Tribe maintains a singular, fixed hormonal strategy focused solely on natural testosterone optimization, while Joi + Blokes provides a multi-pronged, customizable approach across several hormonal, metabolic, and wellness areas. Maximus emphasizes simplicity and consistency, while Joi + Blokes offers breadth and personalization.

How Did We Evaluate Joi + Blokes?

  1. Brand Credibility

    We evaluated Joi + Blokes by looking at its background, services, and customer feedback. The brand, founded by Josh and Katy Whalen in the early 2020s, focuses on personalized hormone optimization, peptide therapy, lab testing, and health coaching for both men (Blokes) and women (Joi) through a telehealth platform.

    Customer feedback played a key role in our evaluation. Joi + Blokes holds a 4.8-star rating on Trustpilot, based on over 1,000+ reviews. Reviewers consistently highlight the smooth lab testing process, thorough consultations, and effective outcomes, noting improvements in energy and sleep.

    We also considered the company's broader credibility. Joi + Blokes is not listed on the Better Business Bureau (BBB), which may reflect its recent establishment or telehealth-focused model rather than its reliability.

    Thus, the combination of high customer satisfaction and the absence of a BBB listing presents a mixed yet largely positive credibility picture, suggesting a brand that is generally well-regarded by its users.

  2. Real User Feedback

    Our evaluation of Joi + Blokes is based on customer experiences reported on Trustpilot throughout 2025.

    We considered feedback on the brand's core offerings, including personalized supplements, HRT programs, lab services, and health consultations.

    Many users highlighted improvements in energy, recovery, and overall wellness, as well as the convenience of daily supplement routines and detailed health insights from consultations. The brand's approach of providing recommendations without pressuring additional purchases was also noted.

    At the same time, we examined criticisms around pricing, subscription clarity, and fulfillment. Several reviews mentioned unexpected costs for advanced lab panels or medications, delays in receiving prescriptions, and occasional communication gaps with health coaches or support staff.

    Some users reported running out of medication earlier than expected or long processing times for compounded prescriptions, suggesting inconsistencies in service reliability.

    The user reviews indicate that Joi + Blokes provides effective guidance and supplementation for many users, but prospective customers should be aware of potential logistical issues and higher costs. The overall experience appears to depend on individual tolerance for these operational challenges.

Frequently Asked Questions

  • Does Joi + Blokes provide free initial lab tests?
    No. Joi + Blokes offers initial and follow-up lab work that involves an additional cost, either billed separately or included in the membership price. These tests are conducted through partner laboratories and are required before the procedure can begin.
  • Does Joi + Blokes have a physical pharmacy location?
    No. All prescriptions accessible through Joi + Blokes are processed through partner compounding pharmacies and shipped directly to the member's address. There are no physical pickup locations or walk-in pharmacy services.
  • Are hormone plans from Joi + Blokes available in pill form only?
    No. Joi + Blokes offers hormone plan formats that include injections, topical creams, or transdermal patches, depending on the prescribed therapy. The delivery method is determined by the clinician based on lab results and plan goals.

Conclusion

Joi + Blokes offers a diagnostics-first, personalized model to address hormone optimization, supplements, peptides, and lifestyle guidance. The brand states that licensed clinicians oversee programs built on comprehensive lab testing, measuring fitness markers such as hormone balance, cardiovascular function, inflammation, and metabolic activity.

Joi + Blokes provides virtual consultations, progress monitoring, and direct communication with a care team to deliver structured, evidence-based programs aimed at improving energy and performance. Continuous oversight allows for adjustments based on updated lab data, providing an adaptive approach not typically available through standardized healthcare models.

Joi + Blokes also comes with some limitations, such as additional out-of-pocket costs beyond membership fees, restricted insurance coverage for most plans, and the absence of in-person consultations. Dependence on compounding pharmacies and frequent lab testing may also be inconvenient or costly for some users.

Before considering the offerings available through the Joi + Blokes platform, it is important to confirm potential medication costs, check insurance eligibility, and determine whether telehealth oversight meets personal care preferences. While Joi + Blokes' approach is grounded in clinical research and individualized planning, outcomes can vary depending on fitness status, adherence, and other lifestyle factors.

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This project was supported in part by NSF Grant IIS-03-25867 (ITR: An Electronic Field Guide: Plant Exploration and Discovery in the 21st Century) and by the Washington Biologists' Field Club.
Any opinions, findings, conclusions or recommendations expressed in this material are those of the authors and do not necessarily reflect the official views, opinions, or policy of the National Science Foundation (NSF).