L-citrulline supplements may help enhance athletic performance by boosting nitric oxide production, improving blood flow, and increasing endurance during workouts. This non-essential amino acid could support cardiovascular health and may help with erectile issues.
Citrulline is a key component of the urea cycle, which may remove ammonia from the body, preventing the negative effects of excessive buildup. Since it's not easily obtained through diet, supplementing with L-citrulline may provide you additional support to maximize its benefits, particularly in reducing ammonia toxicity during exercise.
In this blog post, we've reviewed the best 10 L-citrulline supplements of 2025 to help you find the best option for your fitness goals.
PureBulk L-Citrulline DL-Malate is a blend of the amino acid L-citrulline and malic acid. L-citrulline supports the urea cycle, helping the body eliminate excess ammonia by converting it into urea.
This process also contributes to the internal recycling of L-arginine, which the body uses to generate nitric oxide. Malic acid supports cellular energy through its role in the citric acid cycle, helping facilitate the production of energy in the form of ATP.
This combination may assist with energy and muscular endurance during physical activity. Supplementation with citrulline malate increases ATP production and supports phosphocreatine recovery, both of which are associated with improved muscle output and reduced fatigue. Additionally, the presence of citrulline in the urea cycle may help ease muscle soreness by removing ammonia from muscle tissue after intense training.
The “2:1” ratio in PureBulk's formulation reflects two parts L-citrulline to one part DL-malic acid, delivering 3000 mg per serving—2000 mg from L-citrulline and 1000 mg from DL-malic acid. This balance supports both sustained energy production and muscle recovery when used as part of a regular workout regimen.
As per its official site, Now Foods L-Citrulline delivers 1500 mg of L-citrulline per 2-capsule serving, supporting your body's natural ability to manage nitrogen balance n your body. The makers mention that their L-citrulline formulation may help improve protein metabolism, support immune function, and aid in muscle recovery.
BulkSupplements L-Citrulline Powder may provide 3 grams of L-Citrulline per 1tsp of 3gram serving, supporting physical performance, recovery, and cognitive function. It may help in promoting vasodilation, which improves blood flow and enhances nutrient delivery during intense workouts. This improved circulation can lead to stronger muscle pumps, greater endurance, and quicker recovery. BulkSupplements L-Citrulline might also support the removal of lactic acid and contribute to ATP production, helping reduce post-exercise soreness and restore energy levels.
As per its official site, Nutricost L-Citrulline Malate has a 2:1 ratio of L-citrulline to malic acid in an easy-to-mix powder format. One scoop could provide you with 3 grams of l-citrulline blend. The addition of malic acid may help boost your endurance by assisting in your body's natural energy cycle. Currently, it is available in 300g, 600g, and 1.2kg containers, with each tub including a scoop for simple measuring.
DoubleWood Supplements L-Citrulline may help boost your athletic performance, energy levels, and cardiovascular function. L-citrulline might increase plasma levels of L-arginine and L-ornithine, which contribute to nitric oxide metabolism and ammonia recycling. These processes may promote efficient blood flow and support muscular performance during training.
By enhancing nitric oxide synthesis, L-Citrulline encourages better circulation, improved muscle pumps, and greater endurance. It may also aid aerobic performance by supporting oxygen delivery to working muscles, helping reduce fatigue during extended workouts or physical activity.
One DoubleWood Supplements L-Citrulline bottle contains 210 capsules, providing nearly four months of supply. For daily support, the makers suggest taking two 600 mg capsules with meals. To enhance endurance before a workout, they suggest taking 6 to 8 capsules about one hour prior to exercise.
Horbäach L-citrulline might support your fitness performance with a concentrated daily dose of 2,400 mg of free-form L-citrulline per 3-capsule serving. Delivered in quick-release capsules, this supplement could help you integrate L-citrulline into your fitness routine. This could potentially enhance blood circulation and improve your endurance.
As per its official site, Primaforce L-Citrulline provides 2500 mg of L-citrulline per serving, delivered through two tablets. With 240 tablets per bottle, users receive up to 120 servings, making it convenient for consistent supplementation.
L-citrulline is associated with nitric oxide (NO) production in the body. NO supports vasodilation, which can help improve circulation and support oxygen and nutrient delivery during physical activity. This may contribute to better endurance and reduced muscle fatigue.
The formula includes supporting ingredients like hydroxypropyl methylcellulose, microcrystalline cellulose, and magnesium stearate, aiding in tablet structure and ease of digestion. The maker's suggested use is two tablets daily with 8–12 oz of water.
Zazzee Naturals L-Citrulline may offer a high-potency formula with 1800 mg of L-citrulline per serving, delivered through 180 capsules per bottle. The capsules feature L-citrulline malate, which supports better utilization by the body. The official site mentions that Zazzee Naturals L-Citrulline is 100% vegetarian and avoids unnecessary fillers, binders, or synthetic additives.
It might help in promoting circulation and aiding recovery after intense physical activity. It helps clear ammonia, which may aid in reducing excessive fatigue after your workout sessions.
As per its official site, Healthy Origins L-Citrulline Powder may provide 10.6oz (300g) of the amino acid L-Citrulline, which plays a key role in supporting healthy nitric oxide levels in your body. It could help enhance athletic performance by improving blood flow, boosting oxygen, and delivering nutrients to muscles during intense workouts. L-Citrulline supports the urea cycle, which may help prevent excess ammonia from harming the body. It is priced at $24.99, with a subscription option offering a 15% discount, bringing the cost down to $21.24.
Dorado Nutrition L-Citrulline may help elevate your workout performance by enhancing blood flow, muscular endurance, and recovery. It could help amplify nitric oxide production that may help widen the blood vessels, improving oxygen and nutrient delivery to working muscles. This physiological process might help with stronger muscle pumps, delayed fatigue, and sustained energy output.
One Dorado Nutrition L-Citrulline bottle contains 240 vegan capsules (60 servings). It may help in promoting an anabolic environment through increased circulation, enables more efficient nutrient absorption and accelerates muscle repair, potentially supporting lean muscle mass development. Currently, Dorado L-Citrulline is available for shipping across the United States, Canada, Australia, and the UK.
L-Citrulline supplements may sometimes cause gastrointestinal problems. This issue arises frequently with high-concentration powders or capsules that deliver large doses of L-Citrulline Malate or Free Form L-Citrulline in a single serving. For example, some supplements contain 2,400 mg to 3,000 mg per scoop or capsule serving, which can overwhelm the digestive system of sensitive users or those new to amino acid supplementation.
Product formats like unflavored powder can exacerbate this issue, especially if mixed inconsistently or taken on an empty stomach. They can cause bloating, nausea, loose stools, or abdominal cramps shortly after consumption. These effects are often a byproduct of osmotic changes in the gut due to high amino acid concentrations that draw water into the intestines.
Taking L-Citrulline supplements can lead to a significant drop in blood pressure, which may not be a problem for most people but can be dangerous for those with pre-existing low blood pressure. The supplement may function by increasing nitric oxide production, which causes blood vessels to widen (vasodilation). While this is generally seen as beneficial for circulation, it can exacerbate low blood pressure, leading to symptoms like dizziness, fainting, and weakness.
Though rare, L-Citrulline supplements might cause allergic reactions such as rashes, itching, or swelling. These reactions are usually triggered by specific ingredients, fillers, or additives in the supplement rather than the L-Citrulline itself. For people with sensitivities, these side effects can be uncomfortable and might require discontinuation of the supplement.
When evaluating the best L-Citrulline supplements, we took into account each brand's reputation based on customer feedback, online reviews, and the transparency of the brand.
PureBulk has earned a strong reputation for offering bulk, pure supplements at competitive prices. The brand has an A+ rating on BBB and a 4.6-star rating on Trustpilot. Customers highlight PureBulk's product transparency, high-quality ingredients, and timely customer support, making it a suitable option to consider among some users.
Now Foods also stands out with a well-established history and a strong reputation. The brand holds an A+ rating with the Better Business Bureau (BBB). Now Foods is recognized for its consistent product quality, transparency, and customer satisfaction, making it a trusted name in the supplement industry.
BulkSupplements has earned a solid reputation due to its focus on purity and high-quality supplements. It also holds a B rating from the BBB and a 1.8-star rating on Trustpilot.
Nutricost is known for offering affordable and high-quality products. It boasts an A+ rating on BBB. The brand's strong reputation is supported by its transparency, commitment to third-party testing, and the effectiveness of its products.
Horbaach has a reputable standing with an A- rating from the BBB. Double Wood Supplements is celebrated for its transparency and research-backed formulations. It holds a 3.7-star rating on Trustpilot , with some people mentioning issues with delayed deliveries and dissatisfaction. It also has an A+ rating with the BBB. Customers value Double Wood for its commitment to quality and effective ingredients, making it a trusted option for those seeking high-performance supplements.
Primaforce maintains a good reputation, with a 4.4-star rating on Amazon, the brand receives positive feedback for the effectiveness of its products. While Primaforce does not have an extensive Trustpilot presence, its solid customer ratings may indicate its reliability and performance-oriented approach.
Zazzee Naturals is gaining positive recognition, especially for its clean, vegan-friendly products. Although it lacks a Trustpilot rating, it has been well-received on ConsumerLab, where customers appreciate its natural ingredients and effectiveness. As a newer brand, Zazzee's reputation is steadily growing.
Healthy Origins has a trusted presence in the supplement market. It holds an A+ rating from the BBB but lacks a Trustpilot rating, which limits full visibility into customer feedback. Despite this, the brand is known for its high-quality, science-backed supplements and has a strong following within the health-conscious community.
Dorado Nutrition, though a newer brand, has garnered positive feedback primarily through online forums like Reddit. However, it does not have a presence on either Trustpilot or BBB, making it difficult to assess its reputation fully. Despite this, its focus on product quality and transparency suggests that it could continue to build its customer base.
We evaluated each L-Citrulline supplement based on how much active ingredient is provided in a single serving, as dosage can significantly affect performance results such as blood flow, endurance, and nitric oxide production.
We evaluated Dorado Nutrition as offering one of the strongest capsule-based options with 3000mg of pure L-Citrulline in four capsules. This dose aligns well with clinical recommendations for performance support.
BulkSupplements L-Citrulline also comes with 3000mg of L-Citrulline per serving through a 1 tsp powder scoop. We found this to be potent and well-suited for users who prefer customizable powder formats.
We also found Nutricost L-Citrulline Malate to match the top-tier dosage by offering 3000mg of L-Citrulline Malate 2:1 in one scoop. This ratio may provide a balance between endurance support and absorption speed.
Healthy Origins L-Citrulline provides a fermented L-Citrulline formula, delivering a clean 3000mg per scoop. The simplicity and fermentation focus may appeal to purity-conscious users.
PrimaForce claims to provide 2500mg of L-Citrulline in two tablets, which could be efficient and user-friendly for those wanting optimal potency in fewer pills.
We evaluated Horbaach L-Citrulline next, which offers 2400mg of L-Citrulline through three quick-release capsules. Though slightly below the 2500mg mark, we found it could be used to support daily performance.
Zazzee Naturals L-Citrulline Malate provides 1800mg of L-Citrulline Malate in three veggie capsules. While it's a bit under the recommended range, we considered it moderate and adequate for general health maintenance.
Now Foods citrulline offers 1500mg per serving from two capsules. We noted this as a lighter dose, better suited for beginners or those who want to build up their intake slowly.
Double Wood Supplements L-Citrulline contains just 1200mg of L-Citrulline per serving from two capsules. We found this to be the lowest capsule-based option on the list and potentially less effective for active users.
PureBulk L-Citrulline provides flexibility with a serving size of 3000mg, though it comes without pre-measured servings. We recognized its potency but noted that dosing precision depends on the user's measuring tools.
When evaluating the price and value of the best L-Citrulline supplements, PureBulk offers one of the most affordable options, with its 100g size priced at $6.50. Bulk Supplements also provides a competitive price for its 500g size at $24.97, with a subscription option that brings the cost down to $22.47.
Nutricost's L-Citrulline Malate is priced at $21.97 for 300g, offering a solid value for the amount provided, and includes a 20% discount for subscription purchases. Healthy Origins offers 3g per serving for $19.95, which is another well-priced option.
Zazzee Naturals provides 180 capsules at 1800mg per serving for $18.97, which, although a smaller serving size compared to others, is still reasonably priced.
Dorado Nutrition offers 3000mg per serving at $19.95, offering a higher concentration of L-Citrulline per serving at a competitive price.
Now Foods presents two options, including 90 Veg Capsules (750mg per capsule) for $27.99 and 180 Veg Capsules for $49.99. The larger quantity offers a better value, but the price is higher as compared to other similar product brands.
PrimaForce is priced at $32 for 240 tablets, each containing 2500mg of L-Citrulline, which is on the higher end in terms of price, though it may be suitable for those who prefer tablets over powder.
Horbaach offers a 2400mg per serving product for $15.28, which is a more affordable option with a larger serving size per capsule. Double Wood Supplements offers a smaller dose of 1200mg per serving for $19.95, which might not be the best value for those seeking a higher dosage per serving.
L-citrulline supplements may help enhance athletic performance, improve blood flow, and reduce muscle fatigue. They could also increase nitric oxide production, which supports better endurance and muscle repair.
The L-citrulline products that we discussed in our blog post claim to offer quality and value, with some supplements offering additional benefits like cardiovascular support and reduced soreness.
However, while it's generally safe to take L-citrulline supplements, they might cause mild side effects, including gastrointestinal discomfort and a bitter taste from unflavored powders. To avoid potential issues, it's essential to follow the maker's recommended dosages and consider the formulation that best suits your preferences, including their capsule or powder form, flavored or unflavored options, or options with added malate for endurance support.
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