Amy Myers MD offers physician-formulated products for gut health, immune support, energy, sleep, and metabolic health. The brand follows a functional medicine approach, with products developed to support specific goals. Its products are available individually or as part of protocols and bundles.
This review looks at the brand’s product range, formulation practices, protocols, and manufacturing standards. It also considers the potential benefits and limitations to help you decide whether the brand is a good fit for your needs.
Founded by Amy Myers, MD, the brand keeps its identity around functional medicine principles and nutritional support across targeted fitness goals. Its lineup features products like probiotics, collagen, protein powders, organic greens, and multivitamins.
The brand also organizes selected products into condition-focused protocols, including The Leaky Gut Solution™ Protocol, Autoimmune Solution™ Protocol, and The SIBO Solution™ Protocol.
According to its official website, all products undergo third-party testing and are produced under Good Manufacturing Practices. The manufacturers state that the products remain free from harmful ingredients like gluten, dairy, soy, GMOs, preservatives, and dyes.

According to the official website, Collagen Protein features a mix of Type I and Type III collagen in a hydrolyzed powder format. It delivers essential amino acids, including glycine and proline, to support connective tissue strength, gut lining structure, and joint health.
The formula comes in a hydrolyzed form, which breaks collagen into smaller peptides and makes it easier to digest. Types I and III collagen supply amino acids that help support and strengthen the gut barrier, reduce intestinal permeability, and support digestive comfort. Collagen Protein also provides proline and other collagen-related amino acids, which could support cartilage integrity and mobility while helping reduce joint discomfort. The formula also increases the body’s stores of keratin and collagen, which are the primary structural components behind hair and nails and contribute to their resilience.
The Myers Way® Multivitamin combines vitamins, minerals, and other micronutrients in bioavailable forms, which are intended for better absorption. It features activated B vitamins like B6, B12, and folate, alongside chelated minerals. The formula pairs iodine with selenium to support thyroid and adrenal health, methylation and detoxification pathways, energy metabolism, and immune function.
It further includes mixed carotenoids as a vitamin A source, which could promote immune function, vision, skin health, and neurological function. The makers added vitamin C as an antioxidant, which contributes to normal immune function and collagen production to support skin elasticity.
The Myers Way® Multivitamin also contains TRAACS® chelated minerals, including calcium, magnesium, zinc, and copper in mineral forms bound to organic compounds. They may help support methylation, skin, and hair health.
Leaky Gut Revive® is a gut-focused formula that may support gut barrier integrity, digestive comfort, a healthy gut microbiome balance, and immunity. It contains L-glutamine, which promotes intestinal cell regeneration and tight-junction function, which helps maintain the barrier between the intestinal contents and surrounding tissues.
The makers added deglycyrrhizinated licorice root to the product, which could help lower blood pressure levels and strengthen the protective mucus lining of the digestive tract.
Slippery elm and marshmallow root extract supply mucilage in the formula, a type of soluble plant fiber that soothes the digestive tract while supporting the mucosal lining.
Methylation Support® could help support methylation pathways, liver detoxification processes, digestion, and energy production. The manufacturer states that the formula is beneficial in supporting methylation, especially in cases of MTHFR genetic variants. It combines riboflavin (B2), vitamin B6 (P5P), folate as L-5-methyltetrahydrofolate (L-5-MTHF), vitamin B12, and TMG.
Riboflavin in the product may stimulate the coenzymes FAD and FMN, which participate in energy metabolism and also promote the activity of the MTHFR enzyme. Vitamin B6 in the product functions as a coenzyme in multiple enzymatic reactions, including amino acid metabolism and neurotransmitter synthesis. The makers included folate for its role in participating in essential processes, including one-carbon metabolism, DNA synthesis, and homocysteine metabolism. Vitamin B12 works alongside folate in methionine metabolism and red blood cell and nervous system function.
Liposomal Curcumin features curcumin in a micelle liposomal form, intended to improve solubility and absorption. According to its official website, the formula contains a proprietary mix of liposomal curcumin with curcuminoids, omega-9, d-alpha tocopherol, and beta-carotene.
Curcumin supplies antioxidant compounds called curcuminoids, which could support your body's natural and balanced immune response. It may also help lower free radical buildup, promote digestive health, and strengthen intestinal barrier function. Omega-9 provides monounsaturated fatty acids that contribute to the lipid-based structure of the liposomal delivery system, helping support the dispersion of curcumin in the digestive tract.
According to the official website, ImmuneIG is a dairy-free formula that contains 3,000 mg of ImmunoLin®, a concentrated serum-derived bovine immunoglobulin and protein isolate. ImmunoLin® is a colostrum alternative with bioactive IgG, IgA, and IgM to support communication between your gut and immune system, gut barrier integrity, and digestive function.
Immunoglobulins act in the digestive tract by binding to unwanted pathogens, toxins, and irritants, helping neutralize them before they can contribute to inflammatory responses or affect the gut barrier. The makers state that IgA, IgM, and IgG help provide immune surveillance along the gut lining, while ImmunoLin® may support tight-junction proteins and mucosal barrier function, which help control movement between intestinal cells.
ZenAdapt is formulated to promote relaxation, improve the body’s response to stress, and support restful sleep without causing grogginess. The formula contains KSM-66® ashwagandha root extract, which could help lower elevated cortisol levels in the body. Such effects may help your body respond to occasional stress from fatigue, overwork, or daily demands more efficiently.
The makers further added PEA in the formula, a fatty acid amide that helps maintain a balanced inflammatory response. ZenAdapt also features rhodiola extract, which may optimize stress adaptation and help reduce mental fatigue. Saffron in the product supplies carotenoid compounds such as crocin and safranal, which may help soothe an overactive nervous system.
Organic Greens is a powdered mix that contains organic superfoods. The formula comprises a mix of organic greens and fruits, including spinach leaf, alfalfa leaf, apple fiber, broccoli sprout, kale leaf, and ginger root. Such ingredients may contribute to natural detoxification processes, immune health, adrenal function, focus, and daily nourishment.
The makers further added maca extract in the formula to promote focus and vitality, while the addition of ashwagandha extract could help encourage adrenal function and lower stress levels. Organic Greens also contains ginger root with bioactive compounds like gingerols and shogaols, which may help promote digestion and minimize digestive discomfort.
According to its official website, Probiotic Capsules 100 Billion features 100 billion CFU from 14 probiotic strains to support a balanced gut microbiome, digestive function, bowel regularity, and immunity. The formula includes Lactobacillus strains like L. acidophilus, L. plantarum, and L. rhamnosus. Such strains produce lactic acid, which lowers the local pH and can make the intestinal environment less favorable for some unwanted bacteria.
The makers further added Bifidobacterium strains, including B. lactis, B. longum, and Streptococcus thermophilus, to the product. Bifidobacterium strains are associated with the large intestine and may contribute to bowel regularity, intestinal barrier function, and the production of some B vitamins. Streptococcus thermophilus could help break down lactose and produce compounds that may protect the gut against harmful pathogens.
According to the official website, Dr. Amy Myers (certified physician) personally guides the development of the brand’s product line. That physician-led focus extends across a broad range of areas, including gut health, immune health, thyroid support, detoxification, brain health, and foundational nutrition.
The connection between the physician behind the brand and these different areas gives the portfolio a consistent point of reference, making it easier to understand the thinking behind its formulations. It can give you greater confidence as you explore the brand’s offerings to find products that fit your needs.
Amy Myers MD combines targeted formulas, nutrition guidance, and lifestyle recommendations into step-by-step plans. The brand states that its protocols target specific concerns like leaky gut, Candida overgrowth, SIBO, autoimmune conditions, thyroid health, and gut health. These protocols follow The Myers Way® framework, with each program pairing formulations with meal plans, recipes, food guides, and shopping lists. You do not need to research products, diet changes, or lifestyle recommendations separately, as the brand’s protocols bring these elements together. It may provide you with a more organized means to follow a health-focused routine from one framework.
Amy Myers MD positions its products at a premium price point. A basic grocery-store multivitamin may cost around $15–$20, while The Myers Way® Multivitamin starts at $49.97 and targeted products like ImmuneIG cost $79.97 per bottle. The brand also keeps its approach to multi-step protocols, which means you may require several products when targeting complex concerns like SIBO or leaky gut. A typical routine can include the $49.97 multivitamin, the $57.97 Primal Earth Probiotic, and Leaky Gut Revive at $49.97, pushing the cost around $150–$200 for one month’s supply.
The pricing approach can make it difficult to follow a complete protocol in the long term. You may need to spend hundreds of dollars each month to follow the recommended combination of products, or leave out certain products altogether.
Founded by Dr. Steven Gundry, Gundry MD is built around the philosophy of Holobiotics, which describes the relationship between the human body and its microbiome. Its approach gives particular attention to dietary factors such as lectins, sugars, artificial sweeteners, and other ingredients that it associates with an unfavorable gut environment. Amy Myers MD follows The Myers Way®, a functional medicine framework that places greater emphasis on gut health, inflammatory dietary triggers, autoimmunity, and toxin removal.
In terms of product catalog, Gundry MD features a diverse lineup segmented across formulations, skin and hair products, lectin-free foods, gummy formulas, everyday essentials, bundles, and air purification products. A few signature offerings in its lineup include Bio Complete 3™, Total Restore®, Vital Reds®, Polyphenol Rich Olive Oil™, and Ultimate H2™. Amy Myers features a more function-specific range segmented across multivitamins, organic greens & reds, protein, probiotics, and collagen powder, alongside targeted protocols around SIBO, Autoimmune, Perimenopause, and Leaky Gut support. Some featured products from the brand include The Myers Way® Multivitamin, Leaky Gut Revive®, Collagen Protein (Type 1 & 3 Collagen), and Primal Earth Probiotics.
Gundry MD also uses its product range to reflect its emphasis on microbiome ecology through products offering combinations of prebiotics, probiotics, postbiotics, polyphenols, MCTs, plant extracts, and gut lining support ingredients. Bio Complete 3™ is a notable example because it combines prebiotic, probiotic, and postbiotic components in one formula. Vital Reds® and Polyphenol Rich Olive Oil™ give polyphenols a more prominent role, while MCT Wellness® uses MCTs as a primary component. Amy Myers MD emphasizes specific functional medicine ingredients across its lineup. These often include L-glutamine, DGL, marshmallow root, slippery elm, aloe vera, arabinogalactan, inulin, and other prebiotic fibers, digestive enzymes, and curcumin.
Gundry MD connects its microbiome approach with dietary choices, lectin reduction, polyphenols, and a wider range of lifestyle-oriented products. Amy Myers MD stays more closely tied to The Myers Way®, with products and protocols organized around gut integrity, inflammatory dietary factors, and functional medicine concerns. Gundry MD offers you a broader microbiome-centered ecosystem, while Amy Myers MD provides a more focused functional medicine framework across its product range.
When comparing Pendulum and Amy Myers MD, both brands offer targeted formulations to support diverse fitness goals. However, the brands differ in their product scope, quality control standards, pricing structures, and accessibility.
Pendulum focuses on microbiome science and the relationship between specific microorganisms and areas like gut health, metabolism, glucose regulation, mood, and energy. Amy Myers MD maintains its identity around physician-formulated products, which may target multiple areas such as immunity, thyroid health, foundational nutrition, metabolic health, sleep, stress, and healthy aging.
When it comes to product breadth, Pendulum reflects a specialized focus, with a relatively concentrated selection of probiotics, prebiotics, polyphenols, and microbiome-focused formulas. The brand’s lineup features some core offerings like Metabolic Daily, Akkermansia, Glucose Control, and Polyphenol Booster. Amy Myers MD has a broader catalog that includes probiotics, vitamins, minerals, multivitamins, protein powders, collagen, organic greens and reds, digestive enzymes, omega-3, and methylation products. Some signature offerings include Complete Enzymes, ZenAdapt, Liposomal Curcumin, Leaky Gut Revive®, and Spectrum 5 Collagen®.
Pendulum also differs from Amy Myers MD in how its formulations are positioned. Pendulum emphasizes the use of in-house and next-generation microbial strains, particularly live Akkermansia muciniphila, Anaerobutyricum hallii, and Clostridium beijerinckii. Its approach emphasizes strain specificity, microbiome research, and clinical validation of particular formulations. Amy Myers is more focused on potency, recognizable ingredients, bioavailability, and physician-formulated products. Its probiotic range includes widely researched Lactobacillus and Bifidobacterium strains, with formulas reaching up to 100 billion CFU counts.
Pricing also reflects the different structures of the two catalogs. For example, the core offerings from Pendulum range from approximately $35 to $99, with Polyphenol Booster at $35, Gut Fuel Pouch and Gut Fuel Packets at $40, and Glucose Control at $99. Amy Myers MD features a wider price range, with products like Liposomal Vitamin C, Complete Enzymes, and Probiotic Capsules 100 Billion priced within the range of $25 and $58.
Pendulum prioritizes microbiome specialization, the use of proprietary strains, research-driven formulations, and specialized manufacturing standards. Amy Myers MD prioritizes physician- formulated offerings, broad functional benefit coverage, ingredient quality, and an extensive educational ecosystem.
For assessing Amy Myers MD, we considered the brand’s business identity, operating history, and ratings across independent review platforms. The brand has an established presence in the supplement space and is closely associated with Dr. Amy Myers, MD, and her physician background. Its current reputation highlights both positive and negative aspects.
On Trustpilot, the brand carries a 4.1 out of 5 rating based on 25+ reviews. The brand’s profile indicates user satisfaction with product quality, helpful customer service interactions, and timely delivery. However, some reviews described frustration with product size and price changes, backorders without timely notice, delayed subscription shipments, and difficulty making subscription changes.
The Better Business Bureau provides the brand with an A+ rating, though it is not BBB accredited. A review highlighted the brand’s products as providing no noticeable change or effects, while the user described the packaging as unique.
The brand’s long operating presence, physician-associated identity, and positive user experiences support a degree of credibility. However, concerns about pricing transparency, order fulfillment, subscriptions, and customer support remain areas of improvement.
In evaluating Amy Myers MD, we reviewed the available Amazon reviews for two of the brand’s core offerings, with attention to both reported benefits and concerns.
Leaky Gut Revive® carries a 4.2 out of 5 rating from more than 1,200 reviews. Several users described gradual improvements in digestive symptoms with the formula, including acid reflux, heartburn, and digestion. One user described fewer loose stools and less sensitivity after taking it for at least four months, while other reviews mentioned reduced stomach swelling and feeling better within two weeks.
However, one user described the product as very expensive and questioned the lack of visible third-party testing information, while other users said it tasted unpleasant and needed constant stirring because the final drink could become sludge. A user experienced severe bloating after drinking the formula while also noting dissatisfaction with the refund experience.
The feedback for The Myers Way® Multivitamin follows a similar pattern, with the product having a 4.5 out of 5 rating from more than 460 reviews. Many users experienced increased energy levels, reduced instances of leg cramps, improved sleep, and a reduction in joint discomfort after using the formula. However, a few users experienced acne, oily skin, worsened brain fog, anxiety-like symptoms, and fatigue after using the product.
The available user feedback, therefore, reflects different responses to the same products, with benefits reported alongside practical and personal concerns. A practical precaution is to consider reported sensitivity, usage guidelines, ingredient amounts, and product cost before use, especially for formulas that pair multiple nutrients.
Amy Myers MD provides access to physician-formulated products grounded in functional medicine principles. It also organizes offerings into structured protocols that pair formulas with lifestyle guidance, which may simplify the process of targeting specific goals like gut health integrity or immune support.
However, the brand’s multi-formula protocols may contribute to added financial commitment, as targeting multiple fitness goals typically requires you to pair several products, which could increase costs.
Most products from the brand pair adaptogens, probiotics, digestive enzymes, botanical extracts, or potent vitamins, which might occasionally lead to digestive discomfort, headaches, or allergic reactions. It is advisable to review ingredient labels, the suitability of protocol recommendations, the budget, and dietary considerations. Doing so may help you determine if the brand’s offerings fit your specific needs.
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